Synopsis of recent research by authors named "Megan N Thobe"
- Megan N Thobe's research focuses on the molecular mechanisms underlying tumorigenesis and metastasis, particularly in prostate cancer and the role of receptor tyrosine kinases such as RON.
- Her work highlights the significance of bone metastasis in prostate cancer, elucidating how secondary tumors preferentially localize to bone, which greatly impacts patient morbidity and mortality.
- Thobe also investigates the role of the human DEK proto-oncogene in cancer biology, linking it to the pathways involved in cellular senescence and the effects of high-risk human papillomavirus on cancer progression.