Publications by authors named "Megan Merrihew"
Article Synopsis
- The Ag-specific B cell receptor (BCR) on B lymphocytes has two main functions: it helps generate intracellular signals and facilitates the internalization of antigens for processing.
- Although lipid rafts in the plasma membrane are known to be involved in BCR signaling, their exact role in internalizing Ag-BCR complexes is unclear.
- Research shows that while B lymphocytes can internalize lipid rafts, this mechanism is not the primary pathway for efficient internalization of Ag-BCR complexes, which use different endocytic pathways to reach separate intracellular locations.
