Publications by authors named "Megan M Doyle"
Article Synopsis
- Scientists study how viruses and their animal hosts have changed together over time and how they can jump from animals to humans.
- They used special models to see which newly found viruses from wildlife might be able to infect people, focusing on high-risk areas in Africa, Asia, and Latin America.
- The research shows that new coronaviruses might infect more types of animals compared to other viruses, helping to figure out where to look for potential outbreaks in humans.
Emerging infectious diseases in humans are frequently caused by pathogens originating from animal hosts, and zoonotic disease outbreaks present a major challenge to global health. To investigate drivers of virus spillover, we evaluated the number of viruses mammalian species have shared with humans. We discovered that the number of zoonotic viruses detected in mammalian species scales positively with global species abundance, suggesting that virus transmission risk has been highest from animal species that have increased in abundance and even expanded their range by adapting to human-dominated landscapes.
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- Flaviviruses are causing significant global epidemics and are appearing in new regions, but the factors behind their emergence and spread are not fully understood.
- Researchers have identified potential wildlife reservoirs of flaviviruses and analyzed ecological traits to assess the risk of these viruses transmitting among animal populations and identify outbreak-prone regions.
- By combining data on host variability with ecological and climatic models, the study predicts new potential host species and enhances global surveillance efforts for flavivirus outbreaks in both animals and humans.