Climate change has created unprecedented stresses in the agricultural sector, driving the necessity of adapting agricultural practices and developing novel solutions to the food crisis. (Camelina) is a recently emerging oilseed crop with high nutrient-density and economic potential. Camelina seeds are rich in essential fatty acids and contain potent antioxidants required to maintain a healthy diet.
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November 2021
Our group has found that protein S-glutathionylation serves as an important feedback inhibitor for superoxide (O)/hydrogen peroxide (HO) production by several mitochondrial dehydrogenases. Since cytoplasmic oxidases can also serve as important reactive oxygen species (ROS) sources, we hypothesized that glutathionylation can also inhibit O/HO by these enzymes. We first focused our attention on using a purified xanthine oxidase (XO) of bacterial origin to discern if glutathionylation can shut down ROS production by this enzyme.
View Article and Find Full Text PDFBackground: The WHO Programme for International Drug Monitoring (PIDM) was established in 1968 following the thalidomide disaster. The PIDM has had considerable success in analyzing drug-related adverse event reports, but more limited progress has been made in analyzing vaccine-related reports. In June 2005, the Global Advisory Committee on Vaccine Safety, acknowledging these limitations, called for a global consultation to address the need for improved monitoring and analysis of vaccine-related adverse event reports on an international level.
View Article and Find Full Text PDFThe World Health Organization (WHO) Programme for International Drug Monitoring (PIDM) was initially developed for chemical rather than biological products. The PIDM made considerable achievements in analysing drug-related adverse event reports, progress was more limited for vaccine-related reports. In 2005, the Global Advisory Committee on Vaccine Safety, called for a global consultation to address the need for improved monitoring and analysis of vaccine-related adverse event reports on an international level.
View Article and Find Full Text PDFPurpose: Several randomized trials have found that discharge planning improves outcomes for hospitalized patients. We do not know if adding a clinical nurse specialist (CNS) to physician teams in hospitals that already have discharge planning services makes a difference.
Methods: In 2 teaching hospitals, patients were randomly assigned to regular hospital care or care with a clinical nurse specialist.
Objective: There are not enough pediatric neurologists to meet the many needs of pediatric neurology patients. The Hospital for Sick Children has responded by expanding the nursing role in the pediatric neurology outpatient clinic. The objective of this study was to examine the use of a telephone nursing line in this hospital-based pediatric neurology clinic.
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