Publications by authors named "Megan Lamond"

Background: Kidney disease is fairly unique due to the lack of symptoms associated with disease activity, and it is therefore dependent on biological monitoring. Dried biofluids, particularly dried capillary blood spots, are an accessible, easy-to-use technology that have seen increased utility in basic science research over the past decade. However, their use is yet to reach the kidney patient population clinically or in large-scale discovery science initiatives.

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Article Synopsis
  • Immunoglobulin A (IgA) vasculitis (IgAV), also known as Henoch-Schoenlein purpura, is the most common childhood vasculitis that usually resolves on its own, but can lead to significant kidney issues (IgAV-N) in some patients.
  • Current treatments focus on established kidney involvement, but there's a push for early intervention to prevent inflammation before serious kidney damage occurs.
  • Research is ongoing to identify new therapeutic targets and drugs aimed at preventing kidney problems in children with IgAV-N, as current options like corticosteroids have proven ineffective for this purpose.
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