Publications by authors named "Megan Laffoon"

Introduction: Rapidly urbanizing communities in middle-income countries could be sources of vaccine hesitancy, and may create hot spots of low vaccination coverage. This study characterizes vaccine hesitancy in Shanghai and identifies disparities in vaccine safety and efficacy concerns by residency status-a marker for recent migration into the city.

Methods: Parents of children aged ≤18 years from immunization clinics in Shanghai were enrolled in summer 2019, with the data analyzed during winter 2019-2020.

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Article Synopsis
  • Vaccine pricing varies widely worldwide, with many low- and middle-income countries working together to buy vaccines, while China primarily procures its vaccines domestically.
  • Since 2005, China's vaccine procurement methods have undergone significant changes, notably becoming more localized after 2016, which resulted in higher prices for many vaccines.
  • The current system in China leads to non-mandatory vaccines being several times more expensive than those in countries supported by Gavi and UNICEF, highlighting the need for strategies to lower vaccine prices for public health benefits.
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MitoNEET is a protein that was identified as a drug target for diabetes, but its cellular function as well as its role in diabetes remains elusive. Protein pull-down experiments identified glutamate dehydrogenase 1 (GDH1) as a potential binding partner. GDH1 is a key metabolic enzyme with emerging roles in insulin regulation.

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