Dermatoglyphic indices and minor physical anomalies in patients with schizophrenia and related disorders, their first-degree biological relatives, and non psychiatric controls.

Abnormalities in dermatoglyphic indices and minor physical anomalies (MPAs) are two permanent markers of fetal development that have been studied in schizophrenia. This study sought to: (1) compare select dermatoglyphic indices across patients, first-degree relatives, and non psychiatric controls; (2) assess for associations between dermatoglyphic indices and symptoms in patients and schizotypal features in relatives and controls; and (3) examine correlations between dermatoglyphics and MPAs. The two types of markers were assessed in 62 patients with schizophrenia and related disorders, 36 of their unaffected first-degree relatives, and 47 non psychiatric controls.