Publications by authors named "Megan Hoang"
Background/objectives: While alcoholic beverage consumption increases cancer risk, red wine has been touted as a healthier option. To address this unexplored question, we conducted a meta-analysis to summarize evidence from observational studies.
Methods: A literature search of PubMed and EMBASE through December 2023 identified studies examining wine and cancer risk.
Pyoderma gangrenosum (PG) is a rare inflammatory neutrophilic dermatosis that is difficult to diagnose due to non-specific clinical, laboratory, and histopathologic features. Distinguishing pseudoepitheliomatous hyperplasia (PEH) from squamous cell carcinoma (SCC) is also histopathologically challenging. The connection between PEH and PG is not well recognized, and instances of PG mimicking SCC are rare.
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- Research shows a connection between psoriasis and bipolar disorder (BD), with limited studies specifically addressing the link.
- The review analyzed various studies involving BD patients, lithium's effects on psoriasis, and found that psoriasis may increase the risk of developing BD.
- Lithium therapy might worsen psoriasis symptoms, but inositol supplementation could potentially alleviate these effects, highlighting the need for further investigation.
Introduction: We evaluated the impact of gender on disease severity, health-related quality of life (HRQoL), treatment management, and patient-healthcare professional (HCP) interactions from the perspectives of patients with psoriatic arthritis (PsA).
Methods: Data were collected from a global online patient survey conducted by The Harris Poll (November 2, 2017 to March 12, 2018). Eligible patients were aged ≥ 18 years, with a self-reported diagnosis of PsA for > 1 year, had visited a rheumatologist/dermatologist in the past 12 months, and had reported previously using ≥ 1 conventional synthetic or biologic disease-modifying antirheumatic drug.
Furocoumarins potentiate UVA-induced DNA damage in skin melanocytes.
Biochem Biophys Res Commun
December 2023
Epidemiological studies have found that high citrus fruit consumption was associated with higher risk of skin cancer. Citrus fruits and some vegetables contain furocoumarins, which may interact with ultraviolet radiation to induce skin cancer. We aimed to determine the effects of two furocoumarins, including 8-methoxypsoralen (8-MOP) and 6',7'-dihydroxybergamottin (DHB), on UVA-induced DNA damage in human epidermal melanocytes, the origin of melanoma.
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- Glucagon signaling is crucial for keeping blood sugar levels stable in mammals, and the ARRDC4 protein plays an important role in this process.
- Research shows that mice without the ARRDC4 protein struggle with glucagon responses and gluconeogenesis, leading to lower blood sugar after fasting.
- ARRDC4 also interacts with the glucagon receptor and its expression is influenced by insulin, highlighting its key role in regulating glucose metabolism and connecting insulin and glucagon pathways in the liver.
Introduction: Risk factors for a primary cutaneous squamous cell carcinoma (CSCC) are well-established; however, the host and primary tumor risk factors for subsequent CSCC have not been fully explored.
Methods: We performed a retrospective chart review of patients diagnosed with CSCC in an academic dermatology clinic in Rhode Island from 2016-2019. Logistic regression was used to evaluate the associations between host factors and multiple CSCC and between primary tumor characteristics and the risk of subsequent CSCC.