Publications by authors named "Megan G Sharpe"

Article Synopsis
  • * The review aimed to evaluate discharge opioid prescribing practices for neurosurgical patients and assess whether neurosurgeons are over-prescribing opioids, as existing literature on this topic is limited.
  • * A systematic review identified 23 relevant studies, revealing a mix of over-prescribing and under-prescribing of opioids, highlighting a need for individualized patient care and better quality research to help establish effective prescribing guidelines.
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Guidelines recommend using end-expiration pulmonary pressure measurements to determine the hemodynamic subgroups in pulmonary hypertension. Pulmonary artery wedge pressure (PAWP) determinations averaged across the respiratory cycle (PAWPav) instead of PAWP at end-expiration (PAWPee) and cardiac output (CO) measured by Fick (CO) instead of thermodilution (CO) may affect the hemodynamic classification of pulmonary hypertension. To assess the impact on the pulmonary hypertension hemodynamic classification of the use of PAWPee versus PAWPav as well as CO versus CO.

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Background: Physicians, medical students, and health care professionals are charged with staying current throughout their training. No studies have examined the scope of trauma surgery-related podcasts and videos. Our goal was to characterize and evaluate the growing number of trauma-related podcasts and YouTube channels.

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Article Synopsis
  • Bladder diverticula are generally asymptomatic but can increase the risk of bladder cancer, infections, and stones due to urine stagnation.
  • A study reviewing 764 patients with bladder diverticula found a bladder cancer diagnosis rate of 13.3%, with 35.3% of those having cancer within the diverticula.
  • Male gender and older age were identified as significant risk factors for bladder cancer, while other factors like indwelling catheters and recurrent UTIs did not influence the risk.
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Introduction: This protocol is describing the first ever prospective, mock-efficacy, dose exploration trial design testing the feasibility of administering gabapentin in the acute setting as an intervention for neurorecovery. Gabapentin is an FDA-approved medication for treating seizures and postherpetic neuralgia and is used broadly off-label for neuropathic pain management for many conditions, including spinal cord injury. Emerging data suggests that when given early after spinal cord injury onset and in low-medium doses, gabapentin may have properties that promote recovery of neurological function.

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