Publications by authors named "Megan E Holmes"

Alternative pre-mRNA splicing is a combinatorial process involving SR and hnRNP splicing factors. These proteins can silence or enhance splicing based on their expression levels and binding positions. To better understand their combinatorial and interdependent regulation, computational analyses were performed using HepG2 and K562 cell knockdown and binding datasets from the ENCODE Project.

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Objective: The objective of this review was to examine existing literature and conceptually map the evidence for school-based obesity prevention programs implemented in rural communities, as well as identify current gaps in the literature.

Introduction: Pediatric obesity is a significant public health condition worldwide. Rural residency places children at increased risk of obesity.

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Drunkorexia' is characterized by compensating for alcohol-related calories using physical activity (PA). Drunkorexia is common on college campuses but little is known about the PA behaviors within the drunkorexia paradigm. First-year college students living on campus completed an online survey collecting drunkorexia, PA, and alcohol consumption data.

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Purpose: Movement behaviors (i.e. physical activity [PA], sedentary behavior [SB], and sleep) are intrinsically codependent, an issue resolved using compositional data analysis (CoDA).

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Physical inactivity is linked with several chronic diseases and poor academic outcomes. This study aimed to examine the effect an under-the-desk band would have on middle school students' physical activity level, and academic engagement. Two local middle school classrooms (n = 42, M = 20, F = 22) participated in the study, which was conducted over 14 weeks.

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Rural regions in the United States are home to approximately 15-20% of the country's population. These regions are often characterized by low access to medical care and high rates of disease and death. The literature has detailed the heterogeneous nature of rural health disparities, calling for research detailing regional factors that influence individual-level risk factors such as diet and physical activity.

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Metabolic syndrome (MetS) increases the risk of premature morbidity and mortality. Physical activity (PA) beneficially affects MetS; however, it is unclear if PA types differ among adolescents 12-15 years old, according to their MetS status. This study compared self-reported PA types by MetS status.

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Lifetime sports, such as tennis, provide opportunities for participation throughout the lifespan and has been linked with lower risk of cardiovascular disease, obesity, and depression. The objective of this study was to consider the influence of chronic tennis participation on various parameters of health. Members of the International Tennis Federation (ITF) completed a survey consisting of questions from International Physical Activity Questionnaire (IPAQ), Behavior Risk Factor Surveillance System (BRFSS), Satisfaction With Life Survey (SWLS), and specific tennis participation questions.

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Investigate the relationship between intensities of physical activity and severity of drunkorexia behaviors. First-year college students living in residence halls ( = 127) completed an online survey comprising drinking, drunkorexia, and physical activity. Multiple hierarchical linear regressions were implemented to examine if physical activity intensity correlates to drunkorexia severity.

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Disparities in health and academic achievement affect large cross-sections of the same population subgroups. This study examined the relationship metabolic health and academic achievement in youth "at risk" for school dropout in rural Mississippi. Fifteen adolescents participated in a studio based learning educational summer camp and subsequent follow-up sessions during the regular school year that were aimed at developing knowledge of core curriculum subjects by developing design projects based on the camp STEM-related theme.

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The efficacy of carbohydrate (CHO) ingestion during high-intensity strength and conditioning type exercise has yield mixed results. However, little is known about shorter duration high-intensity exercise such as CrossFit. The purpose of this study was to investigate the performance impact of CHO ingestion during high-intensity exercise sessions lasting approximately 30 min.

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Background: The role of psychosocial stress in the development of obesity and metabolic syndrome is receiving increased attention and has led to examination of whether physical activity may moderate the stress-metabolic syndrome relationship. The current study examined relationships among physical activity, stress, and metabolic syndrome in adolescents.

Methods: Participants (N = 126; 57 girls, 69 boys) were assessed for anthropometry, psychosocial stress, physical activity, and metabolic syndrome variables; t tests were used to examine sex differences, and regression analysis was used to assess relationships among variables controlling for sex and maturity status.

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Track and field events place different demands on athletes and may have an effect on balance. This study investigated the effects of event specialty, gender, and leg dominance on balance among adolescent track and field athletes. Forty healthy adolescent track and field athletes (male = 23, female = 17) categorised into three different groups (sprinter = 20, distance runners = 13, throwers = 7) had their single leg static balance measured with the eyes open and the eyes closed using an AMTI force platform.

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Nutrition is an integral component to any athletes training and performance program. In adults the balance between energy intake and energy demands is crucial in training, recovery, and performance. In young athletes the demands for training and performance remain but should be a secondary focus behind the demands associated with maintaining the proper growth and maturation.

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Objective: To examine the associations between morning cortisol and adiposity in children at baseline and 9-month follow-up.

Methods: Participants included 649 (301 males, 348 females) children (9.6 +/- 0.

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Objective: To evaluate the cross-sectional and longitudinal relationships of morning cortisol with trunk fat and resting blood pressure (BP) in children.

Methods: Participants included 72 children aged 4-10 years (mean 7.4 yrs) for the cross-sectional analysis and 58 for the longitudinal analysis.

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Background: We examined whether physical activity modifies the relationship between stress and the metabolic risk score in 8- to 18-year-old males (n = 37).

Methods: Physical activity (PA) and television (TV)/videogame (VG) use were assessed via accelerometer and questionnaire, respectively. Stress was determined from self-report measures.

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