Publications by authors named "Megan Davis-Fields"
Article Synopsis
- Biofilm infections involve bacterial clusters that are much larger than neutrophils, which can't engulf them fully and must instead consume individual bacteria over time.
- Current methods fail to link the success of neutrophil phagocytosis—complete engulfment of foreign material—to the mechanical properties of the larger bacterial aggregates.
- This study develops a technique using gels with varied mechanical properties to show that higher gel elasticity reduces neutrophil phagocytic success, suggesting that the physical characteristics of target structures affect immune responses.
Article Synopsis
- Biofilms are groups of tiny living things called microbes that stick together and are protected by a gooey substance they make, which is mostly made of sugars.
- In cystic fibrosis patients, infections can last a long time, and scientists have found that certain sugars in the biofilm, like alginate and Psl, help protect these biofilms from medicines and the body's defenses.
- New research shows that Psl makes biofilms tougher and helps them stick together better, which might help them resist attacks from immune cells trying to clear them away.
We evaluated the duration of infectivity of two isolates of avian paramyxovirus-1 using a model distilled water system. Both viruses remained infective for extended periods with 1-log10 reduction times ranging from 370 (4 C) to 6 (37 C) days. Minimal effects related to pH (5.
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