Publications by authors named "Meg E Letton"

Physical activity is essential to interrupt the cycle of deconditioning associated with chronic kidney disease (CKD). However, access to targeted physical activity interventions remain under-supported due to limited funding and specialised staff. Digital interventions may address some of these factors.

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Background: Exercise has the potential to reduce the susceptibility to comorbidity and cardiovascular disease in kidney transplant recipients. However, kidney transplant recipients report lower levels of exercise compared to the general population, prompting an investigation into the barriers and enablers to exercise in this transplant cohort.

Objectives: This systematic review aimed to explore and map the barriers and enablers to exercise in kidney transplant recipients.

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Article Synopsis
  • - Regular exercise is essential to counteract age-related declines in strength, balance, and flexibility, with classical ballet emerging as a fun option for middle-aged and older adults.
  • - A study involving 22 healthy women over 50 showed significant gains in lower limb strength and high adherence rates (95%) during a 10-week classical ballet program, with no reported negative outcomes.
  • - The findings indicate that ballet training can effectively improve strength and balance in older adults, suggesting potential for further research through rigorous randomized controlled trials.
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Diabetic peripheral neuropathy (DPN) affects over half of type 2 diabetes mellitus (T2DM) patients, with an urgent need for effective pharmacotherapies. While many rat and mouse models of T2DM exist, the phenotyping of DPN has been challenging with inconsistencies across laboratories. To better characterize DPN in rodents, a consensus guideline was published in 2014 to accelerate the translation of preclinical findings.

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Background: Regular physical activity is of paramount importance to reduce chronic disease risk. Classical ballet training requires balance, strength, and range of motion. Participation in social ballet classes is increasing.

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