Publications by authors named "Meeri Honkanen"
Background: Studies have shown an association between a reported penicillin allergy and an increased risk of surgical site infection. The risk is due to avoidance of cephalosporins and to the use of alternative classes of antibiotics in surgical prophylaxis. The aim of this study was to examine the safety of using cephalosporins in patients with a penicillin allergy label.
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- - Orthopaedic implants can get infected through bacteria traveling from other body areas after surgery, with most research focusing on prosthetic joints and their common infection sources being skin, heart, and dental issues.
- - The likelihood of developing a periprosthetic joint infection (PJI) during bacteria spread is highest with Staphylococcus aureus and beta-haemolytic streptococci, ranging from 12% to 41% for PJI during Staphylococcus aureus bacteraemia (SAB).
- - There is limited data on the infection risk for other orthopaedic implants beyond prosthetic joints, and typically, only symptomatic infected implants are investigated further rather than asymptomatic ones.
Background: A preoperative risk score, the KLIC score (chronic renal failure [K], liver cirrhosis [L], indication of the index surgery [I], cemented prosthesis [C], and C-reactive protein >115 mg/L), has been developed to predict the risk of treatment failure after early prosthetic joint infection (PJI). This study aimed to validate the KLIC score for the debridement, antibiotics, and implant retention (DAIR) procedure and one-stage revisions in a Northern European cohort.
Methods: Revisions due to early PJI of the hip or knee between January 1, 2008, and September 12, 2021, were identified retrospectively.
Background: Prosthetic joint infection (PJI) treatment decisions are traditionally based on treatment algorithms. There is, however, a lack of evidence to support the choice of these treatment algorithms. Therefore, we aimed to assess the one-year survival after PJI revision and compared different surgical strategies in a single-center setting.
View Article and Find Full Text PDFThe incidence of venous thromboembolism (VTE) for non-hospitalised patients with coronavirus disease-2019 infection has not been very widely studied. 13 019 persons with a positive SARS-CoV-2 nucleic acid amplification test were identified. In total, 447 (0.
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- The study focused on prosthetic joint infections (PJI) after total knee arthroplasty (TKA), examining changes in patient demographics and surgical methods over a 13-year period.
- Researchers identified 384 revision surgeries due to PJI, categorizing them based on treatment strategies and types of infections, while noting no significant changes in patient age or comorbidities.
- Results showed a significant decrease in 2-stage revisions from 57.6% to 6.3%, while 1-stage revisions increased from 12.1% to 43.8%, with Staphylococcus aureus being the most commonly found pathogen.
Background: Cephalosporins are recommended as first-line antibiotic prophylaxis in total joint replacement surgery. Studies have shown an increased risk for periprosthetic joint infection (PJI) when non-cephalosporin antibiotics have been used. This study examines the effect of non-cephalosporin antibiotic prophylaxis on the risk for PJI.
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- Prosthetic joint infection (PJI) poses significant risks after total hip arthroplasty (THA), and the study examined changes in patient demographics and comorbidities over 13 years at a major joint surgery center.
- The research included data from 423 PJI revision surgeries, showing an increase in patients with higher comorbidity (ASA-class 4) and early infection rates between 2008 and 2021.
- Results indicated a rise in 1-stage revisions and infections from Staphylococcus aureus, highlighting the growing difficulty in treating PJIs due to increasing comorbidity burdens among patients.
Background: The risk for developing a periprosthetic joint infection (PJI) during bacteremia is unclear, except for bacteremia. The aim of this study was to examine the risk for developing a PJI during bacteremia and to identify possible risk factors leading to it.
Methods: Patients with a primary knee or hip joint replacement performed in a tertiary care hospital between September 2002 and December 2013 were identified (n = 14 378) and followed up until December 2014.
Purpose: There is no uniform definition for periprosthetic joint infection (PJI). New diagnostic criteria were formulated in an international consensus meeting in 2013 and adopted by Centers for Disease Control (CDC) in 2016. The purpose of this study is to compare the new diagnostic criteria with the old CDC criteria from the year 1992.
View Article and Find Full Text PDFBackground: The use of complementary and alternative medicine is high among children and youth with chronic illnesses, including patients with cardiac conditions. Our goal was to assess the prevalence and patterns of such use among patients presenting to academic pediatric cardiology clinics in Canada.
Methods: A survey instrument was developed to inquire about current or previous use of complementary and alternative medicine products and practices, including indications, beliefs, sources of information and whether this use was discussed with physicians.