Quinoline: Synthesis to Application.

This review aims to provide a comprehensive report on the quinoline ring with respect to its synthesis, reactivity, and therapeutic values. The reactivity of quinoline for the metal, electrophile, and other reactive counterparts defines the shape of the quinoline pharmacophore, which is an important part of this report; moreover, its spectroscopic characteristics have been included herein with suitable illustration. The quinoline and its derivatives have been presented as well as the general synthetic approaches along with the new developments in the catalytic system; the relevant information is also summarized under the various separate activity classes.

Pattern of non-fatal injuries in road traffic crashes in a hilly area: A study from Shimla, North India.

Research Question: What are the various injuries in road traffic crash cases?

Objectives: To study various non-fatal injuries in road traffic crash cases.

Study Design: Hospital based Descriptive study.

Study Population: The study population comprised of 401 consecutive cases of non- fatal injuries involved in road traffic crashes and reported at Indira Gandhi Medical College hospital, Shimla.

Health issues of menopausal women in North India.

Objective: To evaluate the health status, age of menopause, and its symptomatology amongst Himachali middle-aged women.

Materials And Methods: A community based cross-sectional study was done from Jul 07 to Jan 08. A structured questionnaire was given to 100 menopausal women from general community of Himachal Pradesh in Shimla.

Increased hematogones in an infant with bicytopenia and leucocytosis:a case report.

Hematogones are the normal bone marrow constituents of bone marrow in children and their number decreases with age. As hematogones can resemble malignant lymphoblasts by their morphologic features and by expression of an immature B-cell phenotype, an accurate distinction of hematogone-rich lymphoid regeneration from leukemic lymphoblasts is critical for patient care. The increased number of hematogones had been reported in the bone marrow of children recovering from chemotherapy, aplastic conditions, other forms of bone marrow injury, infections like Cytomegalovirus, HIV and immune thrombocytopenia disorders.

Microfilaria in thyroid gland nodule.

Presence of microfilaria in the thyroid gland is a rare finding. Filariasis is a common public health problem in the Indian sub-continent. Most of the cases of microfilaria in thyroid gland reported in the literature are associated with goiter and thyroid neoplasms.

Cytomorphology of a case of primary cutaneous B-cell lymphoma.

Primary cutaneous lymphoma designates a heterogenous group of disorders arising from skin T and B cells with no evidence of extra cutaneous disease at the time of diagnosis and six months thereafter. We report the cytomorphological features of a case of primary cutaneous lymphoma, B cell type in a 60 year old female presenting with multiple large bosselated red coloured swellings all over the scalp. Clinical examination revealed no other swelling or lymphadenopathy.

Clinicopathological profile of an unusual case of chondroid syringoma: a case report.

Chondroid syringoma or mixed tumor of the skin is an uncommon tumor that typically presents as small, solitary, slow growing, firm, subcutaneous or intracutaneous nodule. It presents commonly in the head and neck region. This is a case report of 45-year-old female who presented with multiple masses in the flank, chest wall, arm, -thigh and neck measuring 10, 6, 3.