Synthesis, characterization and antimicrobial activity of 1,5-bis[2-(hydroximino)-1-methyl-3-oxo-butane-1,1-diyl]thiocarbonohydrazide and 1,5-bis[2-(hydroximino) -3-oxo-1-phenyl-butane-1,1-diyl]thiocarbonohydrazide.

1,5-Bis[2-(hydroximino)-1-methyl-3-oxo-butane-1,1-diyl]thiocarbonohydrazide [IV] and 1,5-bis[2-(hydroximino)-3-oxo-1-phenyl-butane-1,1-diyl]thiocarbonohydrazide [V] were synthesized by the reaction of thiocarbonohydrazide [I] with either 3-(hydroximino)-pentane-2,4-dione [II] or 2-(hydroximino)-1-phenyl-butane-1,3-dione [III] in a 1:2 molar proportion, respectively. Compounds [IV] and [V] were characterized by elemental analyses, IR and PMR spectroscopic studies. These newly synthesized compounds have been screened or their antimicrobial activity against S.