Global distribution of pesticides in freshwater resources and their remediation approaches.

The role of pesticides in enhancing global agricultural production is magnificent. However, their unmanaged use threatens water resources and individual health. A significant pesticide concentration leaches to groundwater or reaches surface waters through runoff.

Extract and its Bioactive Component Cinnamaldehyde Show Anti-Tumor Effects Inhibition of Multiple Cellular Pathways.

is a tropical plant with traditional medicinal significance that possesses antimicrobial, antifungal, anti-parasitic, and anti-tumor properties. Here, we have elucidated the anti-tumor effects of extract (CZE) and its bioactive compound cinnamaldehyde (CIN) on oral cancer and elucidated underlying molecular mechanisms. Anti-tumor activities of CZE and CIN were demonstrated by various experiments on oral cancer cells (SCC-4, SCC-9, SCC-25).

Efficacy and safety of rituximab in children with difficult-to-treat nephrotic syndrome.

Background: Rituximab has emerged as an important medication for patients with steroid-dependent or steroid-resistant nephrotic syndrome.

Patients: We report the efficacy and safety of therapy with intravenous rituximab, administered once weekly for 2-4 doses, in 193 patients (mean age 10.9, range 2.