Publications by authors named "Meenakshi Chitkara"

Seasonal variations significantly impact buffalo bull semen production and quality, particularly during the summer months. Understanding the genetic basis of these changes is important for managing bull fertility and improving sperm quality. The present study focused on characterizing and identifying polymorphisms in chromatin remodeling genes, protamines (PRMs) and Transition Nuclear Proteins (TNPs) in Murrah buffalo bulls with varying semen quality due to seasonal effects.

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Background: Goat milk is gaining popularity as a superior alternative to bovine milk due to its closer resemblance to human milk. Understanding the molecular processes underlying lactation is crucial for improving milk quality and production in goats. However, the genetic mechanisms governing lactation in goats, particularly in indigenous breeds like the Jakhrana, remain largely unexplored.

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Article Synopsis
  • - The study investigates the genome sequences of three Indian yak populations and compares them with the Jinchuan yak from China, highlighting the uniqueness and adaptability of Indian yaks in extreme climates.
  • - Researchers found 37,437 runs of homozygosity (ROH) across four yak populations, with the Chinese yaks showing higher inbreeding rates, while Indian yaks exhibited more stable and lower inbreeding levels.
  • - Five genetic hotspots linked to critical traits for survival, such as hair growth and nutrient response, were identified, suggesting strong natural selection for these traits in adapting to environmental challenges.
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Selection of the most stably expressed reference genes is key to monitoring accurate target gene expression across any tissue or cell type. The mRNA in spermatozoa stores valuable information related to changes in spermatogenesis due to variations in environmental conditions, especially during heat stress, which affects various sperm functions. Semen quality in buffalo bulls is significantly influenced by the seasons.

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Semen production and quality are closely correlated with different environmental factors in bovines, particularly for the buffalo (Bubalus bubalis) bulls reared under tropical and sub-tropical conditions. Factors including DNA methylation patterns, an intricate process in sperm cells, have an impact on the production of quality semen in buffalo bulls under abiotic stress conditions. The present study was conducted to identify DNA methylome signatures for semen quality in Murrah buffalo bulls, acclaimed as a major dairy breed globally, under summer heat stress.

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