Clinical characteristics and treatment requirements of children with autosomal recessive pseudohypoaldosteronism.

Introduction: Autosomal recessive forms of pseudohypoaldosteronism are caused by genetic defects in the epithelial sodium channel. Little is known about the long-term outcome and medication needs during childhood and adolescence.

Objective: This study reports a single-centre experience of children affected with this ultra-rare condition over a 37-year period.