This condition was described by Haxthausen in 1934 for the first time; it is one of the diseases explained by hyperkeratosis of the palms and soles. This disease is difficult to diagnose, and patients often complain of such conditions; therefore the authors consider it useful to regularly publish descriptions of clinical cases. Besides involvement of the palms and soles, manifesting by hyperkeratotic layers, painful fissures and itching, the patients with climacteric keratoderma develop metabolic endocrine, neurovegetative, and psychoemotional disorders.
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