Publications by authors named "Medved A"

During the next few decades, changes in rainfall frequency and magnitude are expected to have major impacts on landscape evolution, social, and economic aspects of human society. We focus on seasonal rainfall variations by the end of the twenty-first century to define affected landslide-prone areas, future landslide alerts and the impact of landslides on landscape development in the juncture of the Alpine, Pannonian, and Mediterranean region. A moderate and a worst-case climate scenario from CMIP5 global climate simulations were considered to determine the impact of rainfall on the two most common types of landslides in region, shallow and deep-seated landslides.

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Article Synopsis
  • Electrochemotherapy (ECT) is a targeted treatment for skin and certain internal tumors, but its effects on nearby skeletal muscle tissue haven't been thoroughly studied.
  • In experiments using the mouse muscle cell line C2C12, higher voltages during ECT maximized cell permeabilization and maintained cell viability for up to four days.
  • ECT combined with drugs like bleomycin and cisplatin reduced the viability of muscle cells more significantly in myoblasts than in mature myotubes, with a minor increase in IL-6 indicating early inflammatory responses.
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Surface acoustic waves (SAW) in dynamic magnonic crystals (DMC) are considered for their use to create tunable spin-wave gadgets for processing of microwave signals. To understand the principles of operation of the proposed gadgets, the necessary basic properties of DMC created by a SAW in the structure of "yttrium iron garnet film on a substrate of gallium gadolinium garnet" are given. The prototype of the unique nonreciprocal notch filter working in the range of 3600-4100 MHz at the biasing magnetic field of 640 Oe is fabricated and its main characteristics such as dependences of the frequency and the depth of rejection pits on the frequency and power of the controlling SAW are measured.

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Application of surface acoustic wave resonators with a phase format of an output signal as the thermometric "magnifying glass" is suggested. Possibilities of monitoring and measuring of small changes of temperature from 0.001 K to 0.

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A simulation technique, combining chronic recordings in freely moving alert cats with acute experiments on a nerve muscle preparation, has been designed to estimate fusimotor activity profiles underlying chronically recorded muscle spindle afferent responses to movements. Fusimotor stimulation patterns are iteratively generated and tested for their ability to simulate a target response during reproduction of the movement. The error between a simulated and the target response is incorporated into the current stimulation pattern, to generate the stimulation profile for the next cycle of iteration.

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Cyclophosphamide, given in widely spaced doses, was used in the treatment of a patient with pemphigus vulgaris and a patient with bullous pemphigoid. To our knowledge, this form of therapy has not previously been reported in these two diseases. The distinct advantages of the larger intermittent dose method of cyclophosphamide therapy over the more conventional daily dose regimen are discussed.

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