Introduction: Opioid use disorder is a chronic illness with significant morbidity and mortality. Opioid agonists, like buprenorphine, are commonly used to prevent relapse. Recent changes in buprenorphine legislation are expected to increase prescription and guidelines recommend its continuation during the perioperative period for many patients.
View Article and Find Full Text PDFCanine mammary carcinomas (CMC) are associated with major aggressive clinical behavior and high mortality. The current standard of care is based on surgical resection, without an established effective treatment scheme, highlighting the urgent need to develop novel effective therapies. Vascular endothelial growth factor (VEGF) is a key regulator of tumor angiogenesis and progression in the majority of solid cancers, including human and canine mammary carcinomas.
View Article and Find Full Text PDFPurpose Of Review: Postoperative pain continues to be one of the most common challenges following surgeries. Multimodal analgesia has been of particular focus as non-opioid alternatives have been encouraged due to concerns of the opioid epidemic. Ketamine has been an especially useful adjunct in multimodal pain regimens within the past few decades.
View Article and Find Full Text PDFMechanosensory feedback of the internal reproductive state drives decisions about when and where to reproduce. For instance, stretch in the Drosophila reproductive tract produced by artificial distention or from accumulated eggs regulates the attraction to acetic acid to ensure optimal oviposition. How such mechanosensory feedback modulates neural circuits to coordinate reproductive behaviors is incompletely understood.
View Article and Find Full Text PDFMethicillin-resistant Staphylococcus aureus (MRSA) is a Gram-positive bacterium that causes community-acquired and health care-acquired infections. We previously demonstrated that clay phyllosilicates and customized aluminosilicates display antimicrobial activity against the MRSA strain SQL1. The SQL1 annotated genome reveals a USA300 lineage and contributes critical knowledge of the MRSA virulence factors associated with tissue infection.
View Article and Find Full Text PDFBackground: Environmental conditions affect the quality of the fruits and their organoleptic properties. In low-tech greenhouses, these environmental conditions are frequently not optimal for crops. Therefore, the present study demonstrates the effects of the use of an integrated passive heating and cooling system in a greenhouse located in the Mediterranean area on the quality of pepper fruits.
View Article and Find Full Text PDFspecies are Gram-negative bacteria that can infect both animals and plants. The annotated genome presented is the first for a sp. strain (called CC119) that is a cotton boll pathogen.
View Article and Find Full Text PDFSouthern green stink bug [Nezara viridula (L.)] adults and other pentatomid pests can transmit pathogens (e.g.
View Article and Find Full Text PDFField experiments and supporting laboratory work were conducted to characterize the ability of the verde plant bug, Creontiades signatus (Distant), a boll-feeding sucking bug, to transmit a cotton seed and boll rot bacterial pathogen, Serratia marcescens (Bizio) (Enterobacteriales: Enterobacteriaceae). Serratia marcescens was originally isolated from bolls infested with verde plant bug in south Texas, and a Rifampicin resistant S. marcescens strain was used in transmission and retention experiments.
View Article and Find Full Text PDFReef corals and sea anemones form symbioses with unicellular symbiotic dinoflagellates. The molecular circumventions that underlie the successful intracellular colonization of hosts by symbionts are still largely unknown. We conducted proteomic analyses to determine molecular differences of anemones colonized by physiologically different symbiont species, in comparison with symbiont-free (aposymbiotic) anemones.
View Article and Find Full Text PDFThe horticultural industry demands high-quality resources to achieve excellence in yield and optimal revenues. Nitrogen is a pivotal nutrient to accomplish these goals for plant growth and product quality. However, competition for water in semi-arid regions can force the use of brackish waters, which can impair N uptake.
View Article and Find Full Text PDFSpecial staining and grading of canine liver cytology samples aids in detection of increased copper content. The prevalence of copper in routine diagnostic liver cytology samples, clinical findings associated with high cytologic copper (cCu) grade, and the correlation between cCu grade and histologic findings, including histologic copper (hCu) grade, are unknown. This data may be helpful in ascertaining when to determine a cCu grade and when interpreting cCu grade.
View Article and Find Full Text PDFPreviously, we reported the isolation of Klebsiella pneumoniae subspecies pneumoniae strain Kp 5-1 from a southern green stink bug (Nezara viridula) that is a significant pest of numerous economically important crops. We subsequently sequenced the strains whole genome. Here, we report the presence of a functional plasmid-borne type IV secretion (TFSS) system that was identified using genomic mining of the annotated genome.
View Article and Find Full Text PDFIn many plant species, long-term exposure to elevated CO2 concentration results in a reduction in photosynthetic capacity, known as acclimation. This process is mainly explained by a feedback inhibition mechanism. The supply of a fraction of the nitrogen (N) in the nutrient solution as NH4+ can play an important role in the maintenance of photosynthetic activity and could mitigate the acclimation process.
View Article and Find Full Text PDFAims: To determine whether Venturia effusa, the causative fungal agent of pecan scab, harbours a bacterial symbiont.
Methods And Results: Venturia effusa isolates were maintained on potato dextrose agar amended with antibiotics (chloramphenicol (100 μg ml ) and tetracycline 100 (μg ml )). Genomic DNA extracted from mycelia was used to target eubacterial 16S rDNA.
We investigated the effect of supplying nitrogen, as NO or as NO/NH, on the composition of fruits of sweet pepper (Capsicum annuum L. cv. Melchor) plants grown with different CO concentrations ([CO]): ambient or elevated (800 μmol mol).
View Article and Find Full Text PDFAim: To determine the capacity of the brown stink bug (BSB) (Euschistus servus) to transmit an infective Pantoea agglomerans strain Sc 1-R into cotton (Gossypium hirsutum) bolls.
Methods And Results: A laboratory colony of BSB was maintained on fresh green beans. Either sterile or Sc 1-R contaminated beans were offered to adult insects.
In 1999, crop consultants scouting for stink bugs (Hemiptera spp.) in South Carolina discovered a formerly unobserved seed rot of cotton that caused yield losses ranging from 10 to 15% in certain fields. The disease has subsequently been reported in fields throughout the southeastern Cotton Belt.
View Article and Find Full Text PDFPantoea ananatis is a bacterium with versatile niches that vary from pathogenic to beneficial. We present the genome of strain CFH 7-1, which was recovered from a diseased greenhouse cotton boll previously caged with a field-collected cotton fleahopper (Pseudatomoscelis seriatus). These data will assist in deciphering the infection process.
View Article and Find Full Text PDFThe histone acetyltransferase p300 has been implicated in the regulation of liver biology; however, molecular mechanisms of this regulation are not known. In this paper, we examined these mechanisms using transgenic mice expressing a dominant negative p300 molecule (dnp300). While dnp300 mice did not show abnormal growth within 1 year, these mice have many alterations in liver biology and liver functions.
View Article and Find Full Text PDFObjective: To evaluate and describe the performance during the learning process of risk-detection versus risk-benefit processing in adolescents diagnosed with ADHD.
Method: Thirty-five adolescents with ADHD and 26 paired controls participated. The tests applied are Iowa-type children version paradigm and Stroop test.
Background: Different nitrogen inputs and/or development under adverse water conditions (water stress/low quality and/or high salinity/electrical conductivity), such as those prevailing in Almeria (Mediterranean coast, south-east Spain), may affect overall fruit and vegetable quality. This study evaluated the influence of salinity and nitrogen reduction in hydroponic nutrient solution on strawberry fruit quality and nutritional compounds (Fragaria × ananassa Duch., cv.
View Article and Find Full Text PDF