Publications by authors named "Medioli F"

Objective: People with HIV (PWH) have high risk of liver fibrosis. We investigated the effect of weight gain and metabolic dysfunction-associated steatotic liver disease (MASLD) on liver fibrosis dynamics.

Design: Multicenter cohort study.

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Background: Intravenous drug users (IDUs) have a high risk of developing skin and soft tissue infections such as erysipelas, abscesses, and less frequently necrotizing fasciitis (NF) or gas gangrene. Rarely, the cause of the infection is microorganisms residing in the oral cavity and can lead to life-threatening infections.

Methods: We describe the case of a 43-year-old man intravenous drug user (IDU) who was admitted for intense leg pain following an injection of cocaine at that site.

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Article Synopsis
  • * A specific challenging case of S. maltophilia BSI due to septic thrombosis is presented, where the infection was successfully treated using cefiderocol in addition to levofloxacin.
  • * The treatment plan also included an intra-lock therapy with trimethoprim/sulfamethoxazole to prevent reinfection, as full resolution of the infection source was not achievable, supported by a serum bactericidal assay to confirm the treatment's effectiveness.
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Article Synopsis
  • Carbapenem-resistant Acinetobacter baumannii (CRAB) poses a significant threat in healthcare settings, with over a 40% mortality rate among critically ill patients; this review focuses on the best infection prevention and control (IPC) strategies to combat its spread in hospitals.
  • A critical review of literature from the past 10 years assessed IPC measures in various settings, with the majority of studies centered on ICU outbreaks, showing high mortality rates up to 50%.
  • The review found that while some IPC measures like environmental disinfection were universally applied, others varied significantly by study and setting, emphasizing that targeted 'search and destroy' strategies are key to effective CRAB control.
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Background And Aim: simulation became gradually pivotal in training of health professionals: indeed, it showed an improvement in practical skill of the trainees compared to theoretical lectures. Among others, ACLS (advance cardiovascular life support) courses are now one of the standard learning practices most spread around the world. The primary aim of this study is to evaluate both the level of satisfaction and the clinical thinking that the trainees perceived during an ACLS course.

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Mental retardation and natural sexual development appear to be a more consistent feature in the autosomal rather than in the sex chromosome anomalies. On the contrary the anatomical and functional sexual disfunction characterize the sex chromosome syndromes. An early diagnosis and a better knowledge of the chromosomal abnormalities are important for the social integration and the control of the sexual development and behaviour of this patients.

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An adolescent, presented during 24 months an intermittent bilateral accommodation palsy. All the clinical tests were negative; a few peculiar aspects of the patient's character incited us to carry out, in parallel, a psychological research. The young man proved to be a mixed introvert, with Oedipal and familial problems.

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