Publications by authors named "Mediha Eser"
Background: Despite the progress in the treatment of acute kidney injury (AKI), current curative approaches fail to provide adequate treatment. In this study, we aimed to investigate the possible protective effects of thymosin-β-4(Tβ4) on an ischemic AKI model in rats.
Methods: Rats were randomly assigned into four groups ( 8/group): The control group (sham-operated), the ischemia-reperfusion (I/R) group; renal ischemia (90 min) by infrarenal abdominal aortic occlusion followed by reperfusion (3 h), the Tβ4 + I/R group; treated with Tβ4 before I/R, and the I/Tβ4/R group; treated with Tβ4 just before reperfusion.
Article Synopsis
- The study looked at how a signaling system called Notch is affected in a liver disease model in rats, and how a substance called resveratrol might help.
- Rats were split into four groups: one that got no treatment, one that received a harmful chemical (CCl₄), one that got the chemical plus resveratrol, and one that got only resveratrol.
- The results showed that the CCl₄ group had more signs of liver damage and higher Notch levels, but the group that received resveratrol had less liver damage and lower Notch levels.
Objective. The aim of this study was to investigate the efficacy of beta-aminopropionitrile (BAPN) and prednisolone on the prevention of esophageal damage and stricture formation after caustic esophageal burn. Method.
View Article and Find Full Text PDFDoxorubicin induced nephrotoxicity: protective effect of nicotinamide.
Int J Cell Biol
November 2011
Introduction. Nephrotoxicity is one of the important side effects of anthracycline antibiotics. The aim of this study was to investigate the effects of nicotinamide (NAD), an antioxidant agent, against nephrotoxicity induced by doxorubicin (DXR).
View Article and Find Full Text PDFFor patients with epilepsy, anti-epileptic medication is generally the first line of treatment, but treating pregnant women with epilepsy can be a challenge. Standard anti-epileptic medications have caused developmental abnormalities, so much effort has been put into developing antiepileptic medications with minimal teratogenic effects. In this experimental study, the new-generation anti-epileptic medication levetiracetam and the standard anti-epileptic medication valproic acid were compared in terms of teratogenicity by studying embryonic development in 360 fertile White-Leghorn chicken eggs (conception day 0).
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