Natural course and survival of neuroendocrine tumors of thymus and lung in MEN1 patients.

Context: The natural course and survival of neuroendocrine tumors (NETs) of thymus (Th) and lung in multiple endocrine neoplasia type 1 (MEN1) patients are still unknown.

Objective: Our objective was to assess prevalence, tumor growth, and survival of Th and lung NETs in an unselected MEN1 population with long-term follow-up.

Design: This was an observational study.

No evidence for distinguishing bacterial from viral acute rhinosinusitis using symptom duration and purulent rhinorrhea: a systematic review of the evidence base.

Objective: To evaluate the diagnostic value of symptom duration and purulent rhinorrhea in adults suspected of having acute bacterial rhinosinusitis.

Data Sources: PubMed, EMBASE, and the Cochrane Library.

Review Methods: We performed a comprehensive systematic search on March 28, 2013.