Measured and predicted calorie requirements of adults during recovery from severe burn trauma.

Major burn trauma produces large elevations in metabolic energy expenditure (MEE) during acute care. However, overfeeding can occur and is detrimental to recovery. The formulae often used to estimate caloric support to meet MEE are based on body weight, predicted resting metabolic rate (RMR), body surface area, or the total body surface area burned (BSAB).

Chronic intracerebroventricular CRF infusion attenuates ACTH-corticosterone release.

Bolus intracerebroventricular delivery of corticotropin-releasing factor (CRF) elicits acute responses of both the pituitary-adrenal axis and the sympathetic nervous system. We examined whether these stresslike responses could be maintained over a period of days by central delivery of CRF in nonstressed rats, as would be predicted if this peptide participates in the central nervous system regulation of chronic stress. CRF (4.

In vivo total body electrical conductivity following perturbations of body fluid compartments in rats.

Total body electrical conductivity (TOBEC) provides a rapid and safe noninvasive technique for the assessment of total body water in animals and man. An instrument employing this principle has been shown to measure body water in healthy Sprague-Dawley rats. With the exception of adult obesity in humans, alterations in body fluid compartments that could theoretically affect the utility of conductivity measurements have not been studied.

Enhanced hepatic insulin sensitivity and peripheral glucose uptake in cold acclimating rats.

Cold-exposed rats exhibit hypermetabolism, hyperphagia, and increased glucose oxidation. Their counterregulatory hormone secretion is markedly elevated, while insulin levels fall acutely, gradually returning to basal during acclimation. We assessed both hepatic and peripheral sensitivity to insulin in rats in the basal state and after 5 days of cold (5 C) exposure.

The analysis of glucose kinetics using a single jugular catheter in awake rats.

The rates of glucose production and utilization can be estimated by a primed-constant infusion technique using separate catheters for the infusion of radiolabelled glucose and periodic blood withdrawal. In rats, a carotid artery catheter is most often combined with a jugular or femoral venous catheter in such studies. We presently describe a method which utilizes a single jugular catheter for both infusion and sampling in the awake rat.

Microbiological investigation of meat wholesale premises and beef carcases in Johannesburg.

Microbiological surveillance by swabbing meat wholesaler premises revealed ineffective cleaning and build-up of bacteria. Proper cleaning, sanitation and handling resulted in a vast improvement during 1975-77. Beef samples from the neck of carcases in the wholesale trade were investigated by microbiological methods.

The incidence and sources of penicillin in milk supplied to the city of Johannesburg.

The incidence of penicillin in bulk milk supplies to the city has varied from 1,2% to 2,6% over the past five years, and 3,2% of 366 pasteurised milk samples examined in 1975 were found to contain penicillin. Investigation of the sources revealed numerous instances of producers, milkers and veterinarians who had not acted responsibly in regard to the marketing of milk from treated cows. Details are provided.

Veterinary public health implications of U H T processing of milk.

The introduction of U H T treatment of milk into South Africa raises problems for local public health authorities controlling milk hygiene in their respective areas because of the legislation concerning milk produced and sold for various purposes. It is essential that the raw milk supply be derived from healthy cows with healthy udders, and be produced under sanitary conditions. Uniform control standards are necessary for U.