Clinical outcomes and molecular profile of patients with Carmi syndrome: A systematic review and evidence quality assessment.

Purpose: Carmi syndrome is a rare genetic disorder characterized by junctional epidermolysis bullosa (JEB) and pyloric atresia (PA). We reviewed the clinicopathologic and molecular features of patients with Carmi syndrome to identify predictors of clinical outcome and guide surgical PA repair.

Methods: A PRISMA-compliant systematic literature review of PubMed, CINAHL, and the Cochrane Library was performed.