Term infant brain MRI after ROP treatment by anti-VEGF injection versus laser therapy.

Background: Intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents is used to treat posterior type 1 retinopathy of prematurity (ROP). Recent reports indicate that anti-VEGF therapy may be associated with white matter brain injury, according to animal studies, and neurodevelopmental impairments in children born preterm. We investigated whether type 1 ROP treated with bevacizumab is associated with structural brain injury on infant term magnetic resonance images (MRIs) in very low birth weight infants compared with those treated with laser ablation.

Antioxidant activity of Schiff base ligands using the DPPH scavenging assay: an updated review.

Schiff base ligands, formed from primary amines and carbonyl compounds, are potential antioxidants because they scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals hydrogen atom transfer (HAT) and single electron transfer (SET) routes. This review aims to help design, synthesize, and discuss the antioxidant activity of Schiff base ligands based on their structure. This study critically discussed the solvent effect and the structural changes of Schiff base ligands responsible for DPPH scavenging activity, such as proton donating, electron-donating, and electron-withdrawing substituents, conjugation and ring structure.

Barriers to auditory brainstem response testing under anesthesia.

Objective: Auditory brainstem response (ABR) testing is the gold standard for diagnosis of hearing loss in children who cannot complete behavioral audiometry. Testing under general anesthesia is often recommended when natural sleep ABR and/or behavioral audiometry are unsuccessful. This study aims to determine which demographic and patient factors serve as barriers to receiving this diagnostic testing.

Treatment of Persistent Soiling in Hirschsprung Disease With Antegrade Continence Enemas.

Introduction: Patients with Hirschsprung disease (HD) can experience soiling after their pull-through. We evaluated the use of antegrade continence enema (ACE) for this patient population and investigated the timing and factors associated with getting the patient clean.

Methods: We performed a single-institution retrospective review (from January 2020 to January 2023) of patients with HD and prior pull-through who had persistent soiling, failed laxative treatment or rectal enemas, and were treated with antegrade enemas.

Rabies control in Bangladesh and prediction of human rabies cases by 2030: a One Health approach.

Background: Bangladesh is making progress toward achieving zero dog-mediated rabies deaths by 2030, a global goal set in 2015.

Methods: Drawing from multiple datasets, including patient immunisation record books and mass dog vaccination (MDV) databases, we conducted a comprehensive analysis between 2011 and 2023 to understand the effectiveness of rabies control programmes and predict human rabies cases in Bangladesh by 2030 using time-series forecasting models. We also compared rabies virus sequences from GenBank in Bangladesh and other South Asian countries.

Evaluation of Noise Exposure Levels in Pediatric ENT Operating Rooms.

Objective: Operating room (OR) sounds may surpass noise exposure thresholds and induce hearing loss. Noise intensity emitted by various surgical instruments during common pediatric otolaryngologic procedures were compared at the ear-level of the surgeon and patient to evaluate the need for quality improvement measures.

Study Design: Cross-sectional study.

Ecological risk assessment of microplastics and mesoplastics in six common fishes from the Bay of Bengal Coast.

Plastic particles have emerged as a growing threat to both ecosystems and human well-being, as they are being ingested and accumulate at different trophic levels. However, microplastic and mesoplastic contamination and its risk to coastal and marine water fish have not been well studied, particularly in the northern Bay of Bengal. In this study, the presence of small-scale plastic particles (micro- and meso-sized) in the gastrointestinal tract (GIT) and muscles of six edible fish species from the northern Bay of Bengal Coast were identified and analyzed.

Antibiotic Overtreatment of Presumed Urinary Tract Infection Among Children with Spina Bifida.

Objective: To identify factors associated with overtreatment of presumed urinary tract infection (UTI) among children with spina bifida using such criteria.

Study Design: A retrospective review of children with spina bifida (age <21 years) evaluated in the Emergency Department (ED) at a single institution was performed. Patients with a urinalysis (UA) performed who were reliant on assisted bladder emptying were included.

Impact of upper airway obstruction management in Robin Sequence on need for myringotomy tubes.

Objective: Investigate an association between upper airway obstruction (UAO) management in Robin Sequence (RS) and need for bilateral myringotomy and tubes (BMT).

Methods: Retrospective chart review of RS patients treated at a tertiary free-standing pediatric hospital from 1995 to 2020 was performed. Patients were grouped based on airway management: conservative, tracheostomy, tongue-lip adhesion (TLA), and mandibular distraction osteogenesis (MDO).

Improving Outcomes through Implementation of an Infant Spinal Anesthesia Program for Urologic Surgery Patients.

Introduction: Spinal anesthesia has a long history as an effective and safe technique to avoid general anesthesia in infants undergoing surgery. However, spinal anesthesia was rarely used as the primary anesthetic in this population at our institution. This healthcare improvement initiative aimed to increase the percentage of successful spinal placements as the primary anesthetic in infants undergoing circumcision, open orchidopexy, or hernia repair from 11% to 50% by December 31, 2019, and sustain that rate for 6 months.

Predicting Failure of Conservative Airway Management in Infants with Robin Sequence: The EARN Factors.

Objective: Evaluate infants with Robin Sequence (RS) who were successfully treated with conservative airway measures alone vs. those who failed and eventually underwent surgical airway intervention after a protracted course of conservative management.

Design: Retrospective review of prospectively gathered database.

Humoral immune responses in different stages of wound healing in Black Bengal goats.

Objective: The current study was carried out to assess the humoral immune responses according to age at different stages of wound healing in Black Bengal goats (BBG).

Materials And Methods: Apparently, healthy BBGs ( = 20) were collected and divided into five groups based on their age: Group A (control, 3 years), Group B (3 to 5 years), Group C (2 to <3 years), Group D (1 to <2 years), and Group E (<1 year). Except for control, all BBGs were allowed to have artificial surgical wounds, and follow-up data were collected from day 0 to 21.

Antimicrobial, antioxidant, and cytotoxic properties of endophytic fungi isolated from Thysanolaena maxima Roxb., Dracaena spicata Roxb. and Aglaonema hookerianum Schott.

Background: Endophytic fungi have recently been recognized as an impressive source of natural biomolecules. The primary objective of the research was to isolate fungal endophytes from Thysanolaena maxima Roxb., Dracaena spicata Roxb.

Modification of Bulk Density, Flow Property and Crystallinity of Microcrystalline Cellulose Prepared from Waste Cotton.

The most affordable type of tablet is the immediately compressible tablet, which uses microcrystalline cellulose (MCC), a popular pharmaceutical excipient, as a filler or binder. To make it compatible with different active drugs and excipients, we tried to change some physical properties of the MCC. In the current study, we used a chelating agent to pretreat the waste cotton before pulping, bleaching, and finally, hydrochloric acid degradation with a concentration of 2N at 100 °C temperature for 20 min to prepare MCC.

Predicting failure of detection of peritonsillar abscess with ultrasound in pediatric populations.

Purpose: Some patients require additional imaging following ultrasound (US) to definitively diagnose a peritonsillar abscess (PTA), delaying intervention and disease resolution. We seek to evaluate patient characteristics which may predispose to a secondary imaging requirement to diagnose PTA, in order to better understand ultrasound limitations and predict who will require additional studies.

Materials And Methods: Retrospective chart review of patients with an US for suspected PTA between July 2017 and July 2020.

Botulinum Toxin to Improve Scar Quality in Cleft Lip Repair: A Systematic Review.

Objective: Cleft lip repair (CLR) can be complicated by hypertrophic scar or keloid. Botulinum toxin type A (BTA) may improve postoperative scarring by reducing muscle tension and cytokine activity at the scar site. This systematic review analyzes the available evidence regarding the effect of BTA on scar quality after CLR.

Prevalence of Prohibited Questions during Plastic Surgery Residency Interviews.

Unlabelled: Despite rules set forth by the National Resident Matching Program and American Association of Medical Colleges (AAMC), prohibited questions during the residency interview process are well documented. This study describes the prevalence of these encounters by surveying residency applicants to integrated plastic and reconstructive surgery (PRS) programs for the 2022 match cycle.

Methods: An anonymous 16-question REDCap survey was distributed to 2022 cycle applicants of a single PRS program.

Exploring the factors contributing to increase in facility child births in Bangladesh between 2004 and 2017-2018.

Background: Although Bangladesh has gained rapid improvement in births at health facilities, yet far behind to achieve the SDG target. Assessing the contribution of factors in increased use of delivery at facilities are important to demonstrate.

Objective: To explore the determinants and their contribution in explaining increased use of facility child births in Bangladesh.