To Determine the Role of Human Papillomavirus in Oral Cancer-A Prospective Study.

Introduction: Human papillomavirus (HPV) has been implicated in several studies pertaining to oral squamous cell carcinoma (OSCC) in the last several decades. Infection with human papillomavirus (HPV), particularly HPV16 and 18, is the leading cause of squamous cell carcinoma of the neck (SCCHN).

Methodology: We selected an adequate number of subjects with the same parameters for both the case and the controls based on detailed case histories, specifically taking into account the adverse habits (tobacco in any form and alcohol) that each subject had recorded.