A rare homozygous ALX4 mutation in a Bangladeshi girl with frontonasal dysplasia type-2 (FND2).

Background: Frontonasal dysplasia type-2(FND2), a rare phenotypically variable and heterogeneous developmental anomaly resulting from mutation of the ALX4 gene, is primarily characterized by malformation of the skull and facial skeleton. This study was designed to showcase a clinical, imaging, and genetic analysis of FND2 in a consanguineous family of Bangladeshi origin.

Methodology: Clinical imaging and whole genome sequencing of mother, father and patient was done by using Nextera DNA flex library preparation kit (Illumina, USA) using Novaseq 6000 next generation sequencer to find out ALX4 mutation which causes FND2 in patient.

Green synthesis of silk sericin-embedded silver nanoparticles and their antibacterial application against multidrug-resistant pathogens.

Background: The green synthesis strategy of metallic nanoparticles (NPs) has become popular due to being environmentally friendly. Stable silver nanoparticles (AgNPs) have been synthesized by natural products such as starch, soy protein, various extract of leaves, barks, and roots functioning both as reducing and stabilizing agents. Likewise, silk sericin (SS) is a globular protein discarded in the silk factory might be used for NP synthesis.

Assessing the effect of regularization on the molecular properties predicted by SCAN and self-interaction corrected SCAN meta-GGA.

Recent regularization of the SCAN meta-GGA functional (rSCAN) has simplified the numerical complexities of the SCAN functional, alleviating SCAN's stringent demand on the numerical integration grids to some extent. The regularization of rSCAN, however, results in the breaking of some constraints such as the uniform electron gas limit, the slowly varying density limit, and coordinate scaling of the iso-orbital indicator. Here, we assess the effects of regularization on the electronic, structural, vibrational, and magnetic properties of molecules by comparing the SCAN and rSCAN predictions.

Validation of the Bangla version of Beck Depression Inventory-II.

Background: Beck Depression Inventory (BDI-II) is a widely used valid instrument to assess the severity of depression in clinical and normal settings. To meet the necessity of a standard scale for measuring depression among above 265 million Bangla speaking population around the world, this scale was translated and validated.

Methods: Two translations of BDI-II into Bangla were prepared, and then, two back translations were done by medical and language experts in parallel.

"Stealth cranioplasty:" A novel endeavor for symptomatic adult Chiari I patients with syringomyelia: Technical note, appraisal, and philosophical considerations.

Aim And Objective: In this article, we describe a novel technique of reconstruction of posterior fossa by cranioplasty with use of preshaped titanium mesh following posterior fossa decompression (PFD) for Chiari malformation type I (CMI) with syringomyelia (SM) in symptomatic adults.

Materials And Methods: Eleven patients underwent limited PFD and expansive cranioplasty with preshaped titanium mesh, what we term as "Stealth Cranioplasty" (SCP), following arachnoid preserving duraplasty (APD) and hexagonal tenting of the duraplasty with the cranioplasty (HTDC) for the management of symptomatic adult CMI with SM. All these patients had syringes extending from 3 to >10 vertebral levels.

Recurrent Lateral Ventricular Enterogenous Cyst: A Report of an Extreme Rare Case.

The patient was a 45-year-old man with a progressive headache. Evaluation in detail revealed it as a case of left lateral ventricular space occupying lesion (SOL) resembling choroid plexus papilloma. A left parietal craniotomy was done and the lesion was removed completely through intraparietal approach.

An analytical coupled technique for solving nonlinear large-amplitude oscillation of a conservative system with inertia and static non-linearity.

Based on a new trial function, an analytical coupled technique (a combination of homotopy perturbation method and variational method) is presented to obtain the approximate frequencies and the corresponding periodic solutions of the free vibration of a conservative oscillator having inertia and static non-linearities. In some of the previous articles, the first and second-order approximations have been determined by the same method of such nonlinear oscillator, but the trial functions have not been satisfied the initial conditions. It seemed to be a big shortcoming of those articles.