Effect of channeling agents on the release pattern of theophylline from kollidon SR based matrix tablets.

The purpose of the present study was to investigate the effect of channeling agent on the release profile of theophylline from Kollidon SR based matrix systems. Matrix tablets of theophylline using Kollidon SR which is plastic in nature were prepared by direct compression process. NaCl and PEG 1500 were used as channeling agents.