Publications by authors named "Md Rasel Uddin"

Objectives: Dengue emerged as a significant health threat in endemic regions in recent years. However, inconsistent diagnostic accuracy in sequential dengue infections necessitate improved testing methods to ensure effective management of dengue cases. Here, we evaluated a portable, rapid, and sensitive molecular assay-reverse transcriptase recombinase polymerase amplification assay (RT-RAA)-utilizing a mobile suitcase laboratory to detect infections in suspected dengue cases in Bangladesh.

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Objectives: As post kala-azar Dermal Leishmaniasis (PKDL) threatens the success of the Visceral Leishmaniasis (VL) elimination initiative, we aimed to investigate the PKDL burden, including an active search for PKDL in leprosy-negative skin lesion cases. We also investigated their health-seeking behavior and perceived level of stigma.

Methods: This was a cross-sectional survey among inhabitants in the VL-endemic villages of the five most VL-endemic upazilas.

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Background: COVID-19 has largely impacted the management of Visceral leishmaniasis (VL), like several other Neglected Tropical Diseases. The impact was particularly evident in Lower and Middle-Income countries where the already inadequate healthcare resources were diverted to managing the COVID-19 pandemic. Bangladesh achieved the elimination target for VL in 2016.

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The study aimed to explore epidemiological, serological, and entomological aspects of visceral leishmaniasis (VL) in suspected new VL foci and assess the knowledge, attitude, and practices of the community living in the alleged new VL foci. The study investigated new visceral leishmaniasis (VL) cases reported between 2019 and 2020 in four sub-districts (Dharmapasha, Hakimpur, Islampur and Savar) where we tested 560 members using the rK39 rapid test and conducted vector collections in six neighbouring houses of the index cases to assess sandfly density and distribution, examined sandflies' infection, and determined the spatial relationship with VL infection. Furthermore, we highlighted the importance of early detection, and community awareness in controlling the spread of the disease.

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The dataset of Bangladeshi sign language words (BdSLW) is rare. Though there are lots of datasets of BdSL sign alphabets, numbers, or characters, there are not enough datasets of sign words. This is the first dataset about sign words of BdSL according to the author(s) knowledge.

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Article Synopsis
  • The isothermal nucleic acid amplification techniques, particularly the recombinase polymerase amplification (RPA) assay, have made it possible to detect pathogenic DNA directly in clinical samples, presenting a new approach in diagnostics over real-time PCR.
  • A multi-country evaluation study was conducted in Bangladesh, India, Nepal, and Sri Lanka on clinical samples from patients with various forms of leishmaniasis to compare the diagnostic effectiveness of the RPA assay against real-time PCR.
  • While real-time PCR showed higher sensitivity in detecting visceral leishmaniasis (VL) and post-kala-azar dermal leishmaniasis (PKDL), the RPA assay showed promise but was less sensitive for cutaneous leishmaniasis (CL
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