Purification and characterization of Taxol and 10-Deacetyl baccatin III from the bark, needles, and endophytes of Taxus baccata by preparative high-performance liquid chromatography, ultra-high-performance liquid chromatography-mass spectrometry, and nuclear magnetic resonance.

Taxol and 10-Deacetyl baccatin III are major taxanes in the bark, needles, and endophytes of Taxus baccata. The current study aimed to develop a process for their separation from different matrices. Crude taxoid was prepared by extraction of samples with methanol, followed by partitioning with dichloromethane and precipitation with hexane.

Spatial accessibility to healthcare facilities in coastal region of Bangladesh.

Though equal and easy accessibility to healthcare facilities are a fundamental right, people of the coastal region often get poor accessibility to healthcare facilities. This research aimed to assess the spatial accessibility to healthcare facilities in the coastal region of Bangladesh. Patuakhali district was selected as the study area.