Publications by authors named "Md Nazmul Hasan Zilani"

Recent research has looked at various macroalgae species as dietary components or feed additives for a variety of fish species due to their nutritional value. The objective of this study was to examine the impact of Najas indica, a macroalgae extract, on the growth performance, proximate composition, and metabolic activities of monosex tilapia (Oreochromis niloticus), while also isolating the compounds present. Three distinct solvents (n-hexane, ethyl acetate, and ethanol) were used to extract bioactive compounds from a coarse powder of macroalgae after drying and grinding, and gas chromatography-mass spectrometry (GC-MS) analysis was used to detect bioactive compounds.

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Article Synopsis
  • * The study focused on developing a multi-epitope vaccine against the pathogen Stenotrophomonas maltophilia by analyzing 81 of its complete genomes, identifying key proteins associated with virulence.
  • * Promising results from the vaccine's design showed effective antigenic properties and stable binding to TLR-4, indicating potential for future research, though further testing in mouse models is necessary to confirm immune protection.
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Article Synopsis
  • Herbal remedies, particularly the plant Crotalaria quinquefolia, have traditional uses in treating various ailments, including lung infections and fever.
  • The research investigated the plant's bioactive compounds and their neuropharmacological effects using tests on mice and advanced analytical methods like HPLC and GCMS.
  • Results indicated that C. quinquefolia has significant antioxidant properties and active compounds that may offer therapeutic benefits for neurological conditions, especially Alzheimer's disease.
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Huntington's disease (HD) is a gradually severe neurodegenerative ailment characterised by an increase of a specific trinucleotide repeat sequence (cytosine-adenine-guanine, CAG). It is passed down as a dominant characteristic that worsens over time, creating a significant risk. Despite being monogenetic, the underlying mechanisms as well as biomarkers remain poorly understood.

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Ethnopharmacological Relevance: The traditional use of plants for medicinal purposes, called phytomedicine, has been known to provide relief from pain. In Bangladesh, the Chakma indigenous community has been using Allophylus villosus and Mycetia sinensis to treat various types of pain and inflammation.

Aim Of The Study: The object of this research is to evaluate the effectiveness of these plants in relieving pain and their antioxidant properties using various approaches such as in vitro, in vivo, and computational techniques.

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Silver nanoparticles (Ag NPs) play a pivotal role in the current research landscape due to their extensive applications in engineering, biotechnology, and industry. The aim is to use fig ( Linn. f.

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Traditional medicinal plants have played a promising role in the human health system. In folklore medicine, L. is used to treat fever, pain, eczema, impetigo, lung infections, scabies.

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Diabetes mellitus (DM) is a metabolic disorder arising from insulin deficiency and defectiveness of the insulin receptor functioning on transcription factor where the body loses control to regulate glucose metabolism in β-cells, pancreatic and liver tissues to homeostat glucose level. Mainstream medicines used for DM are incapable of restoring normal glucose homeostasis and have side effects where medicinal plant-derived medicine administrations have been claimed to cure diabetes or at least alleviate the significant symptoms and progression of the disease by the traditional practitioners. This study focused on screening phytocompounds and their pharmacological effects on anti-hyperglycemia on Swiss Albino mice of n-hexane, ethyl acetate, and ethanol extract of both plants and as well as the in-silico investigations.

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An evaluation of the expression and predictive significance of the gene in brain lower-grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several transcriptome servers were used to measure the differential expression of the targeted gene and search mutations and copy number variations. GENT2, Gene Expression Profiling Interactive Analysis, Onco-Lnc, and PrognoScan were used to figure out the survival rate of LGG cancer patients.

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Dengue is a infection transmitted through mosquitoes of the genus, which is known to occur in over 100 countries of the world. Dengue has no available drugs for treatment; CYD-TDV is the only vaccine thus far approved for use by a few countries in the world. In the absence of drugs and a widely approved vaccine, attention has been focused on plant-derived compounds to the discovery of a potential therapeutic for DENV.

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Lectins are a unique group of nonimmune carbohydrate-binding proteins or glycoproteins that exhibit specific and reversible carbohydrate-binding activity in a non-catalytic manner. Lectins have diverse sources and are classified according to their origins, such as plant lectins, animal lectins, and fish lectins. Marine organisms including fish, crustaceans, and mollusks produce a myriad of lectins, including rhamnose binding lectins (RBL), fucose-binding lectins (FTL), mannose-binding lectin, galectins, galactose binding lectins, and C-type lectins.

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(Wall.) is extensively used in traditional medicine for the treatment of various diseases including rheumatism, kidney problems, jaundice, urinary tract disorders, fever, and pain. The present study was designed to explore new lead compound(s) to alleviate pain, pyresis, and diarrhea from methanol, ethyl acetate, and n-hexane extracts of (Wall.

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Ethnopharmacological Relevance: Medicinal plants are sources of chemical treasures that can be used in treatment of different diseases, including inflammatory disorders. Traditionally, Heritiera littoralis, Ceriops decandra, Ligustrum sinense, and Polyscias scutellaria are used to treat pain, hepatitis, breast inflammation. The present research was designed to explore phytochemicals from the ethanol extracts of H.

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Ethnopharmacological Relevance: Consumable herbs play a basic part in sustenance and human health. Traditionally, Colocasia gigantea Hook (Araceae) is used to treat fever, infection, wounds healing, drowsiness, tuberculosis, stomach problems etc. AIM OF THE STUDY: The study aspired to identify bioactive compounds, to evaluate anti-inflammatory and analgesic potentials of edible herb C.

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Background: Consumption of vegetables has been proven to be effective in the prevention of different diseases. Traditionally edible aerial part of Pisum sativum L. subsp.

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Background: Breast cancer, a hereditary or heterogeneous sporadic disease, is the most common cancer in women worldwide. The tumor suppressor TP53 gene has been found to be the most commonly mutated genes in many types of human cancers, including breast cancer. This study aimed to investigate the association of codon 72 polymorphism of TP53 gene with breast cancer risk in Bangladeshi females.

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