Vancomycin conjugated iron oxide nanoparticles for magnetic targeting and efficient capture of Gram-positive and Gram-negative bacteria.

Drug conjugated iron oxide magnetite (FeO) nanoparticles are of great interest in the field of biomedicine. In this study, vancomycin (Van) conjugated magnetite (FeO) nanoparticles were envisioned to capture and inhibit the growth of bacteria. Hydrophobic FeO nanoparticles were synthesized by using co-precipitation of ferrous (Fe) and ferric (Fe) ions following a surface modification step with oleic acid as stabilizers.

Triethyl-ammonium bis-(2-oxido-2,2-diphenyl-acetato-κO,O)anti-monate(III).

The coordination around the Sb atom in the title compound, (C(6)H(16)N)[Sb(C(14)H(10)O(3))(2)], is fourfold in a pseudo-trigonal-bipyramidal pattern in which one of the equatorial sites is occupied by the stereoactive lone pair of electrons. The four ligating atoms comprise the hydoxylate and carboxyl-ate O atoms from two independent benzilate ligands, each of which forms a five-membered chelating ring, spanning an axial and an equatorial site about the Sb atom. The hydroxy-late atoms occupy the two equatorial sites, and the carboxyl-ate atoms are in the pseudo-axial sites; the O-Sb-O angle is 147.