Publications by authors named "Md Iqbal Ahmed"
Introduction: Viral infections are the predominant cause of acute hemorrhagic conjunctivitis (AHC) across the globe. From July to August of 2023, a large-scale conjunctivitis outbreak was witnessed in India, affecting a large number of individuals. The present study was initiated to identify the causative agent responsible for the AHC outbreak in Kalburgi district of Karnataka state.
View Article and Find Full Text PDFBackground Ventilator-associated pneumonia (VAP) is defined as pneumonia that develops 48 hours or more after endotracheal intubation or tracheostomy and is brought on by infectious organisms that are not present or incubating during mechanical ventilation. Multidrug-resistant organisms originate primarily from the hospital environment and significantly contribute to ventilator-associated pneumonia. These organisms pose a severe threat, leading to a higher mortality rate due to their resistance to more potent antibiotics.
View Article and Find Full Text PDFfruit extract modulated antioxidant gene expression, prevented oxidative stress and ameliorated kidney dysfunction in isoprenaline administered rats.
Biochem Biophys Rep
July 2021
Article Synopsis
- The study examined the protective effects of fruit extract against renal damage caused by isoprenaline (ISO) in rats, highlighting increased oxidative stress markers and decreased antioxidant enzyme function due to ISO.
- Fruit extract, known for its high antioxidant content, successfully reduced levels of harmful oxidative stress markers like MDA, NO, and APOP in the kidneys of rats treated with ISO.
- Both fruit extract and atenolol were found to significantly reduce kidney inflammation and tissue damage, potentially preventing kidney dysfunction by modulating inflammation and oxidative stress-related gene expressions.
Phytol (PYT) is a diterpene member of the long-chain unsaturated acyclic alcohols. PYT and some of its derivatives, including phytanic acid (PA), exert a wide range of biological effects. PYT is a valuable essential oil (EO) used as a fragrance and a potential candidate for a broad range of applications in the pharmaceutical and biotechnological industry.
View Article and Find Full Text PDFCorrelations between Risk Factors for Breast Cancer and Genetic Instability in Cancer Patients-A Clinical Perspective Study.
Front Genet
February 2018
Article Synopsis
- Molecular epidemiological studies reveal that genetic instability from DNA damage plays a key role in breast cancer diagnosis and treatment outcomes.
- This study analyzed 150 individuals, including breast cancer patients undergoing chemotherapy and radiotherapy, to assess the impact of sociocultural and lifestyle factors on genetic instability.
- Findings indicate that older age, smoking, and exposure to ionizing radiation contribute to higher levels of DNA damage, suggesting that these risk factors may exacerbate genetic instability in non-cancerous cells during treatment.
Three novel analogues of the cyclic pentapeptide sansalvamide A have been synthesised in high yield. A leucine residue in the lead compound is replaced with either a glycine, β-alanine or GABA residue, and the corresponding linear precursor peptides are found to cyclise with dramatically improved efficiency. This correlates with an increase in the effective molarity (EM) of the cyclisation reactions.
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