Recent Advances in the Application of Glycan-Modified Self-Assembled Monolayers.

Glycans have many important roles in human health and disease in processes such as infection, fertilization, cellular development, cellular adhesion, cancer metastasis and immune system response. The presentation of glycan structures on surfaces for screening of their interaction with protein binding partners, interactions with individual cells, and development of bioassays is an actively developing field. Self-assembled monolayers (SAMs) of glycan terminated alkanethiols on gold have found application in many of these areas.

Nanomaterials for Biosensing Lipopolysaccharide.

Lipopolysaccharides (LPS) are endotoxins, hazardous and toxic inflammatory stimulators released from the outer membrane of Gram-negative bacteria, and are the major cause of septic shock giving rise to millions of fatal illnesses worldwide. There is an urgent need to identify and detect these molecules selectively and rapidly. Pathogen detection has been done by traditional as well as biosensor-based methods.

A systematic study of segregation for Zn(x)Bi(1-x) liquid binary alloys.

We have investigated the segregating properties of Zn(x)Bi(1-x) liquid binary alloys through the thermodynamic route that involves both energy of mixing and entropy of mixing. The perturbation approach is used for effective numerical calculations. Results of our calculations agree well with corresponding experimental data for energy and entropy of mixing in the mixed state.