Stability, challenges, and prospects of chitosan for the delivery of anticancer drugs and tissue regenerative growth factors.

Chitosan, a biopolymer derived from chitin, offers significant potential for regulated anticancer drug administration and tissue regeneration growth factors, owing to its biocompatibility, low toxicity, biodegradability, and little immunogenicity. Moreover, its structure can be extensively modified, for example, to create scaffolds, hydrogels, nanoparticles, and membranes, allowing it to be engineered precisely to achieve specific outcomes However, the therapeutic utilisation of chitosan is impeded by significant challenges, such as its inadequate hemocompatibility, durability, and uniformity in commercial manufacturing. Additionally, there is insufficient research offering a thorough examination of the capabilities, limitations, and challenges related to chitosan as carriers for anticancer drugs and growth factors.

Fabrication of Bio-Based Composite Materials for Antimicrobial Cotton Fabric With Microbial Anti-Adhesive Activity.

The development of multifunctional cotton fabrics that are stain-resistant, antimicrobial, and easy to clean has sparked scientific interest as well as practical usefulness, owing to its medical and healthcare applications. The purpose of this study was to fabricate self-cleaning and antimicrobial cotton for final use by soaking the cotton fabric in nonfluorinated hybrid formulations based on quaternary chitosan-silane using the sol-gel process. The fluorine-free cotton fabric demonstrated high self-cleaning behavior and outstanding bacterial killing efficacy against E.