Publications by authors named "Md Esharuzzaman Emu"
Article Synopsis
- - The study examined how glycosaminoglycans (GAGs) affect the viscoelastic properties of corneal tissue from humans and pigs, aiming to inform new treatments for conditions linked to GAG and proteoglycan changes.
- - Researchers used an enzyme to reduce GAG content in corneal samples and analyzed their structure and mechanical properties through specific assays and rheometry.
- - Findings showed that GAG depletion led to a notable increase in interfibrillar spacing, while the shear stiffness of the corneal samples was influenced by the applied strain; this research highlighted the significant role of GAGs in the mechanical behavior of corneal tissues.
The stiffening effect of corneal crosslinking (CXL) treatment, a therapeutic approach for managing the progression of keratoconus, has been primarily investigated using uniaxial tensile experiments. However, this testing technique has several drawbacks and is unable to measure the mechanical response of cornea under a multiaxial loading state. In this work, we used biaxial mechanical testing method to characterize biomechanical properties of porcine cornea before and after CXL treatment.
View Article and Find Full Text PDFEffect of corneal collagen crosslinking on viscoelastic shear properties of the cornea.
J Mech Behav Biomed Mater
September 2022
The cornea is responsible for most of the refractive power in the eye and acts as a protective layer for internal contents of the eye. The cornea requires mechanical strength for maintaining its precise shape and for withstanding external and internal forces. Corneal collagen crosslinking (CXL) is a treatment option to improve corneal mechanical properties.
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