Successful Treatment of MDR Meningitis in a Young Adult Patient With Intraventricular and Intravenous Polymyxin B-Tigecycline Based Combinations: A Case Report.

Multiple drug resistance to infection treatment is a great challenge for neuro-intensivists due to poor drug penetration through the blood-brain barrier (BBB). Fortunately, the intraventricular administration of polymyxin-B and tigecycline seems to be effective; there are few case reports demonstrating the effectiveness of such treatments. Here, we report the case of a 24-year-old male who presented with fever and neck rigidity after intracranial drainage following lung infection caused by MDR .

An Study on the Mechanical Stability, Spin-Dependent Electronic Properties, Molecular Orbital Predictions, and Optical Features of Antiperovskite AInN (A = Co, Ni).

Structural, mechanical, spin-dependent electronic, magnetic, and optical properties of antiperovskite nitrides AInN (A = Co, Ni) along with molecular orbital diagram are investigated here by using an density functional theory (DFT). The mechanical stability, deformation, damage tolerance and ductile nature of AInN are confirmed from elastic calculations. Different mechanical anisotropy factors are also discussed in detail.