Publications by authors named "Md A H Khan"

Article Synopsis
  • * Positive correlations were found among traits such as storage root weight and foliage weight, indicating potential for effective phenotypic selection, while principal component analysis identified key traits contributing to the overall genetic variance in the genotypes.
  • * The study identified two main genotypic clusters with Cluster I showing superior trait performance, while within Cluster II, further variations were observed, alongside significant genetic influences on traits as shown by the REML model, suggesting potential for selective breeding.
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Background: Severe acute malnutrition (SAM) can be diagnosed using weight-for-height Z-score (WHZ) and/or mid-upper arm circumference (MUAC). Although some favor using MUAC alone, valuing its presumed ability to identify children at greatest need for nutritional care, the functional severity and physiological responses to treatment in children with varying deficits in WHZ and MUAC remain inadequately characterized.

Objective: We aimed to compare clinical and biochemical responses to treatment in children with 1) both low MUAC and low WHZ, 2) low MUAC-only, and 3) low WHZ-only.

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The dataset extensively examines the factors considered when choosing sweet potato genotypes, considering various characteristics. Notably, Moz1.15 demonstrated the highest marketable root yield at 46.

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Article Synopsis
  • - In Bangladesh, sweet potato ranks as the fourth most important carbohydrate source but suffers from issues of yield and stability, prompting researchers to employ various selection methods to identify better-performing genotypes that maintain quality traits.
  • - Through multiple selection methods and a multi-environment trial, researchers identified 71 superior sweet potato genotypes from an initial pool of 351, eventually narrowing it down to 11 top-performing genotypes to optimize yield and quality.
  • - Utilizing advanced statistical models like linear mixed models and the WAASBY index, the study determined that specific genotypes (H20, H37, H8, and H41) excelled in key metrics, such as marketable root yield and nutritional content, indicating a reliable selection
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The dataset focuses on evaluating the performance of 17 sweet potato varieties (G) released by the Bangladesh Agricultural Research Institute (BARI) in terms of storage root yield and stability across five locations (E) in Bangladesh-Gazipur, Bogura, Jamalpur, Jashore, and Chattogram. The result revealed that BARI Mistialu-12 exhibited the highest average storage root yield at 45.35 t/ha, closely followed by BARI Mistialu-16 at 44.

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The dataset explores the impact of waterlogging stress on sesame plants during the pre-flowering stage, recognizing its global impact on crop yield and the identification of tolerant genotypes using the MGIDI index. Carried out in Bangladesh, the research assesses the survival status, grain yield, and stress tolerance indices of 40 sesame genotypes, revealing that twelve of them demonstrated resilience under 72 h of waterlogging stress at the pre-flowering stage. There were variations in genotypic grain yield, and G15 exhibited the highest yields, recording 5.

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Introduction: Renal fibrosis associated with inflammation is a critical pathophysiological event in chronic kidney disease (CKD). We have developed DM509 which acts concurrently as a farnesoid X receptor agonist and a soluble epoxide hydrolase inhibitor and investigated DM509 efficacy as an interventional treatment using the unilateral ureteral obstruction (UUO) mouse model.

Methods: Male mice went through either UUO or sham surgery.

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A study was conducted in five regions of Bangladesh, specifically Gazipur, Bogura, Jamalpur, Jashore, and Chattogram, each characterized by suitable agro-ecologies for sweet potato cultivation. The purpose of this data article was to demonstrate the correlations between traits and the selection of stable varieties based on the multi-trait stability index (MTSI). The data indicated a direct link between multiple characteristics and both the yield and factors contributing to yield.

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This paper is primarily concerned with data analysis employing the nonlinear least squares curve fitting method and the mathematical prediction of future population growth in Bangladesh. Available actual and adjusted census data (1974-2022) of the Bangladesh population were applied in the well-known autonomous logistic population growth model and found that all data sets of the logistic (exact), Atangana-Baleanu-Caputo (ABC) fractional-order derivative approach, and logistic multi-scaling approximation fit with good agreement. Again, the existence and uniqueness of the solution for fractional-order and Hyers-Ulam stability have been studied.

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Article Synopsis
  • Lipoid proteinosis is a rare genetic skin disorder passed down through families, manifesting in various body systems, and inherited in an autosomal recessive way.
  • A case study details a 10-year-old boy with notable symptoms like hoarseness, photoaging skin changes, and a swollen tongue who also exhibits widespread skin lesions.
  • Genetic analysis identified a new mutation in the extracellular matrix protein 1 gene that resulted in a stop codon, marking the first documented instance of this mutation associated with lipoid proteinosis in Bangladesh.
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The incidence of ureter obstruction is increasing and patients recovering from this kidney injury often progress to chronic kidney injury. There is evidence that a long-term consequence of recovery from ureter obstruction is an increased risk for salt-sensitive hypertension. A reversal unilateral ureteral obstruction (RUUO) model was used to study long-term kidney injury and salt-sensitive hypertension.

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Background And Purpose: Diabetic nephropathy is a common complications related to high morbidity and mortality in type 2 diabetes. We investigated the action of the dual modulator, PTUPB, a soluble epoxide hydrolase and cyclooxygenase-2 inhibitor against diabetic nephropathy.

Experimental Approach: Sixteen-week-old type 2 diabetic and proteinuric obese ZSF1 rats were treated with vehicle, PTUPB or enalapril for 8 weeks.

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Background And Objectives: Use of mid-upper arm circumference (MUAC) as a single screening tool for severe acute malnutrition (SAM) assumes that children with a low weight-for-height score (WHZ) and normal MUAC have lower risks of morbidity and mortality. However, the pathophysiology and functional severity associated with different anthropometric phenotypes of SAM have never been well characterized. We compared clinical characteristics, biochemical features, and health and nutrition histories of nonedematous children with SAM who had (1) low WHZ only, (2) both low WHZ and low MUAC, or (3) low MUAC only.

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Unplanned industrialization and improper management of wastes and gases into open surfaces are affecting the agricultural lands causing heavy metal pollution. This study monitored a suburban industrial zone located beside the Dhaka Export Processing Zone (DEPZ) at the Dhaka district in Bangladesh. We studied the heavy metal (Fe, Mn, Cr, Cu, Ni, Co, Zn, Pb, and Cd) concentration in the agricultural soils, plants, and in the atmospheric particulate matter (PM).

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In this work, a TiO-coated GaN nanowire-based back-gate field-effect transistor (FET) device was designed and implemented to address the well-known cross-sensitive nature of metal oxides. Even though a two-terminal TiO/GaN chemiresistor is highly sensitive to NO, it suffers from lack of selectivity toward NO and SO. Here, a Si back gate with C-AlGaN as the gate dielectric was demonstrated as a tunable parameter, which enhances discrimination of these cross-sensitive gases at room temperature (20 °C).

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Article Synopsis
  • The CHoBI7 mHealth program was a study conducted in Dhaka, Bangladesh, focusing on improving diarrhea treatment and outcomes in households caring for diarrhea patients over a 12-month period.
  • Participants were divided into three groups: one receiving standard rehydration messages, and two groups receiving additional health services, either through mHealth or home visits.
  • Results showed that both mHealth interventions significantly reduced the prevalence of diarrhea in young children and improved growth outcomes compared to the standard message group.
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In the last two decades, GaN nanostructures of various forms like nanowires (NWs), nanotubes (NTs), nanofibers (NFs), nanoparticles (NPs) and nanonetworks (NNs) have been reported for gas sensing applications. In this paper, we have reviewed our group's work and the works published by other groups on the advances in GaN nanostructures-based sensors for detection of gases such as hydrogen (H), alcohols (R-OH), methane (CH), benzene and its derivatives, nitric oxide (NO), nitrogen dioxide (NO), sulfur-dioxide (SO), ammonia (NH), hydrogen sulfide (HS) and carbon dioxide (CO). The important sensing performance parameters like limit of detection, response/recovery time and operating temperature for different type of sensors have been summarized and tabulated to provide a thorough performance comparison.

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Background: During the time a diarrhea patient presents at a health facility, the household members of the patient are at higher risk of developing diarrheal diseases (> 100 times for cholera) than the general population. The Cholera-Hospital-based-Intervention-for-7-Days (CHoBI7) is a health facility-initiated water treatment and handwashing with soap intervention designed to reduce transmission of diarrheal diseases between patients and their household members. The present research aimed to (1) develop a scalable approach to integrate the CHoBI7 intervention program into services provided at government and private health facilities in Bangladesh; and (2) tailor the intervention program for the household members of all diarrhea patients, irrespective of the etiology of disease.

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Natural abundances of stable nitrogen and carbon isotopes (δN and δC) can vary with both dietary intake and metabolic (specifically catabolic) state. In low-income countries, weaning is a period of dietary transition from milk to plant-based foods and a high-risk period for malnutrition. We explored how diet and malnutrition impact hair δN and δC in young children by an observational, cross-sectional study in Cox's Bazar District, Bangladesh [255 children, 6-59 months with 19.

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Internet of Things applications require ultra-low power, integrable into electronic circuits and mini-sized chemical sensors for automated remote air quality monitoring system. In this work, a highly sensitive and selective detection of nitrogen dioxide (NO) has been demonstrated by functionalizing gallium nitride (GaN) submicron wire with titania (TiO) nanoclusters. The two-terminal GaN/TiO sensor device was fabricated by top-down approach.

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In this study, electrical characteristics of MoTe field-effect transistors (FETs) are investigated as a function of channel thickness. The conductivity type in FETs, fabricated from exfoliated MoTe crystals, switched from p-type to ambipolar to n-type conduction with increasing MoTe channel thickness from 10.6 nm to 56.

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Toxic gases, such as NO, SO, H₂S and other S-containing gases, cause numerous harmful effects on human health even at very low gas concentrations. Reliable detection of various gases in low concentration is mandatory in the fields such as industrial plants, environmental monitoring, air quality assurance, automotive technologies and so on. In this paper, the recent advances in electrochemical sensors for toxic gas detections were reviewed and summarized with a focus on NO₂, SO₂ and H₂S gas sensors.

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The problem of double-diffusive natural convection of Al2O3 -water nanofluid in a porous triangular enclosure in presence of heat generation has been studied numerically in this paper. The bottom wall of the cavity is heated isothermally, the left inclined wall is non-isothermal and the right inclined wall is considered to be cold. The concentration is higher at bottom wall, lower at right inclined wall and non-isoconcentration at left inclined wall of the cavity.

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Arachidonic acid metabolites have a myriad of biological actions including effects on the kidney to alter renal hemodynamics and tubular transport processes. Cyclooxygenase metabolites are products of an arachidonic acid enzymatic pathway that has been extensively studied in regards to renal function. Two lesser-known enzymatic pathways of arachidonic acid metabolism are the lipoxygenase (LO) and cytochrome P450 (CYP) pathways.

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The A(2B) adenosine receptor (AR) has emerged as a unique member of the AR family with contrasting roles during acute and chronic disease states. We utilized zinc-finger nuclease technology to create A(2B)AR gene (Adora2b)-disrupted rats on the Dahl salt-sensitive (SS) genetic background. This strategy yielded a rat strain (SS-Adora2b mutant rats) with a 162-base pair in-frame deletion of Adora2b that included the start codon.

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