Serotonergic facilitation of facial motoneuron excitation.

The effect of serotonin (5-HT) on motoneurons located in the facial nucleus of the rat was investigated in the present study. Microiontophoretic application of 10--200 nA pulses of 5-HT lasting from 1 to 10 min failed to excite facial motoneurons. However, small amounts of 5-HT facilitated the subthreshold and threshold excitatory effects of iontophoretically applied glutamate on these cells.

Comparative physiology of the high-pressure neurological syndrome--compression rate effects.

The effect of compression rate on onset of high-pressure convulsions has been studied in 14 vertebrate species, as well as in 10 mouse strains and 4 rat strains. Compression rate effects were observed in 9 of the 14 species. They appear to be independent of exposure temperature, correlate only very loosely with phylogenetic position, and appear to reflect species-specific compensatory mechanisms grafted onto an underlying convulsion-producing effect of high hydrostatic pressure.

Improvement of linear accelerator depth-dose curves.

A semiempirical analytic description of the accelerator depth-dose curve is described along with its physical explanation. The results of Monte Carlo calculations are presented and compared with experimental data to test this model. Calculations were made for different atomic number (Z) materials used as x-ray targets and flatteners, with the results showing that medium-Z materials are the logical choice.

Photon and electron response of silicon-diode neutron detectors.

The photon response of silicon-diode neutron detectors is analyzed theoretically and measured in the 15-25-MeV region. The main mechanism for producing a response in the diode is shown to be the displacement of silicon atoms by scattering of electrons. If the photon source is an electron accelerator target, the response is mostly due to electrons originating in the target with a smaller contribution from electrons produced in the diode by photons generated at small angles to the beam.

Childhood IQ's as Predictors of Adult Educational and Occupational Status.

IQ's between 3 and 18 years of age were used to predict attained education and occupational status after 26 years of age. By the second grade these predictive correlations approached those that have been obtained with contemporaneous adult IQ's, especially for occupational status. However, they were not high enough for practical purposes requiring long-term prediction for individual normal children.

Spinal interneurons in the baroreceptor reflex arc.

The zona intermedia of the cat thoracic spinal cord was explored with metal microelectrodes in an attempt to locate interneurons within the pathway that mediates the spinal component of baroreceptor-induced sympathoinhibition. Twenty-nine neurons whose discharges were interrupted during occlusion of the common carotid arteries were found in the vicinity of the intermediomedial nucleus (IMM). The spontaneous discharges of 10 of these units were correlated in time with the R wave of the ECG.

Differential effectiveness of informal group procedures in weight control.

This article is the latest in a series that deals with psychological factors connected with obesity and its management in women members of the TOPS ("Take Off Pounds Sensibly") organization. Successful weight losers have MMPI profiles that differ from those of non-losers, and both show "normalization" of MMPI profiles and improvement in weight control after 16 weeks of group therapy. The present investigation attempted to assess the effectiveness of different types of nonprofessional "therapy" (the interactions of members at local TOPS chapter meetings) in helping members to achieve greater weight control.

The interfering effect of distracting stimuli on the infant's memory.

Infants 3 1/2 months of age were assessed for the possible role of the dissimilarity of the distracting stimulus to the originally learned standard in a modified familiarization-distraction-test paradigm. When data for all subjects were analyzed, there was no evidence that the distraction had any interfering effect at all on the memory for the original standard. However, specialized analyses suggested that interference varied with the likelihood that subjects actually encoded the distracting stimuli might govern the probability or extent that an infant encodes the distracting stimulus rather than affecting the interference process directly.

Imitation of live and televised models by children one to three years of age.

The results of these studies indicated that children younger than 1 year possess the cognitive capability of translating a perception of a novel action into their own behavior. However, the likelihood of imitation varied as a function of the nature of the target behavior. For example, actions requiring direct social commerce with the examiner were imitated less frequently than simple motor behaviors with objects, and reproducing gestures was more common than vocalizations.

Identification and discharge patterns of spinal sympathetic interneurons.

Sympathetic interneurons, in the vicinity of the intermediolateral cell column of the cat thoracic spinal cord, were identified by determining whether the probability of spontaneously occurring unitary discharge was correlated in time with the R wave of the ECG. Fifteen units which could not be antidromically activated by stimulation of the cervical sympathetic nerve exhivited a positive post-R wave relationship. The discharge patterns of these cells were distinctly different from those of antidromically identified preganglionic neurons.

Differential effect of baroreceptor reflexes and clonidine on frequency components of sympathetic discharge.

The effects of the baroreceptor reflexes and clonidine on the 3 and 10 Hz components of spontaneously occurring renal sympathetic nervous discharge (SND) were studied in the cat. The proportion of 3 : 10 Hz SND was assessed by selective filtering and integration of activity in the 2-4 Hz and 9-11 Hz frequency bands. Baroreceptor denervation increased activity in both frequency bands while significantly lowering the 3 : 10 Hz ratio.

Nonpsychotic personality disturbances: a re-evaluation and reclassification.

The classical notion of neurosis as the prototypical form of nonpsychotic personality disturbance must be rejected in favor of the categories of (a) personality pattern disturbance and disorder of life style, and most especially, (b) character disorder. Category (a) would include schizoid, paranoid, and cyclothymic personality pattern disturbances and compulsive and hysteroid personality as disorders of life style. Each of these would occupy one end of a 'psychotoid' continuum, at the other end of which would be a familiar type of psychosis such as paranoid schizophrenia or pseudoneurotic schizophrenia.