Teaching the uptake and distribution of halothane. A computer simulation program.

A computer aided learning program for teaching the kinetics of uptake and distribution of the inhalational anaesthetic halothane is described. The program is based on a seven-compartment model which simulates the action of halothane on ventilation and on the cardiovascular system. The program is available to the student in four forms: one with no changes in circulation or respiration, one with the cardiovascular effects of halothane included, one with respiratory effects only, and one with both of these effects combined.

Evaluation of a computer simulation program for teaching halothane uptake and distribution.

A pilot evaluation of a simulation program used during a tutorial for the teaching of uptake and distribution of the inhalational anaesthetic halothane shows a highly significant improvement in the students' answers after the tutorial using a 'before and after' questionnaire. The students showed an understanding of the program's display and model limitations. This encourages the further use of the program.

The extent of reflux of unconjugated 14C-cholic acid from the liver in subjects with normal liver function.

An improved understanding of bile acid physiology is a prerequisite for the construction of an acceptable model for describing plasma clearance of bile acids. The aim of this study was to determine the extent of reflux unconjugated cholic acid from the liver to the plasma in subjects with normal liver function. The clearance of a bolus injection of unconjugated 14C-cholic acid was studied in four subjects using samples collected simultaneously from a peripheral and a hepatic vein.

The child guidance clinic: Catalyst and coordinator in community treatment of the psychotic child.

Over a period of four years a child guidance clinic has maintained a program for the treatment of psychotic children in the community. A total of 27 community agencies has assisted with the care of 25 children. The primary role assumed by the clinic was that of catalyst and coordinator of the other agencies' work rather than the usual role of treatment of children in relative isolation.