Publications by authors named "McKinley Thomas"

Ewing sarcoma (ES) represents the second most common primary osseous malignancy in children and young adults, most often occurring in the diaphysis of the long bones. While rare, ES can present as an osseous tumor of the ribs and/or chest wall. These tumors are known as Askin's tumors and most commonly present with symptoms resembling pneumonia.

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Vascular graft infections are a well-described complication of loop arteriovenous grafts (AVGs) placed for hemodialysis access and are reported to occur in 0.5% to 6.0% of AVGs.

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Objective: In the United States, deaths among pedestrians have increased dramatically since 2009 relative to other vulnerable road users, with substance use described as an important risk factor. This study aimed to explore blood alcohol concentrations (BAC g/dL) among pedestrian fatalities in the United States between 2016 and 2020. Exploring the presence of alcohol among pedestrian cases will support targeted interventions designed to reduce risk.

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Background: Patient-centered care necessitates an appreciation of one's socioeconomic status and its influence on health and well-being.

Purpose: We explored how student attitudes toward poverty changed as a result of participation in an interprofessional service-learning experience.

Methods: Students from 6 health profession programs participated in an interprofessional military-sponsored free health care event serving nearly 8000 individuals from our community.

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Though U.S. motor vehicle crashes as a whole have decreased over the past few years, fatalities among vulnerable road users have increased.

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Human adipose-derived stromal vascular fraction (hSVF) cells are an easily accessible, heterogeneous cell system that can spontaneously self-assemble into functional microvasculatures in vivo. However, the mechanisms underlying vascular self-assembly and maturation are poorly understood, therefore we utilized an in vitro model to identify potential in vivo regulatory mechanisms. We utilized passage one (P1) hSVF because of the rapid UEA1+ endothelium (EC) loss at even P2 culture.

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Acquiring sufficient amounts of high-quality cells remains an impediment to cell-based therapies. Induced pluripotent stem cells (iPSC) may be an unparalleled source, but autologous iPSC likely retain deficiencies requiring correction. We present a strategy for restoring physiological function in genetically deficient iPSC utilizing the low-density lipoprotein receptor (LDLR) deficiency Familial Hypercholesterolemia (FH) as our model.

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Background And Objectives: As a response to the growing prevalence of chronic disease, models of chronic care have emerged as salient approaches to address dynamic health care changes and to manage the burden of suffering of these diseases. Concurrently, there has been a growing call to address chronic disease management within medical school curricula. This article describes the development and evaluation of a curricular intervention designed to prepare students to integrate patient-centered care with an understanding of the patients' community, provide care within rural settings, and experience clinical education specific to chronic disease management.

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Background: Routine handwashing has been proven to decrease incidence of health care-associated infections, including methicillin-resistant Staphylococcus aureus (MRSA), spawning numerous attempts to "advertise" its importance. However, most control measures fail to evaluate systematically the efficacy of handwashing initiatives. The purpose of this study was to implement a hand hygiene program in an academic medical center, utilizing visual cues developed with periodic input from hospital personnel.

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Frozen dinners prepared by a caterer were reported to have been spoiled. Microbiological testing of samples was performed, and a survey of time-temperature exposures (during preparation, storage, delivery and reheating) was conducted of procedures duplicating those at the time the spoiled food was prepared. Growth of spoilage bacteria was not inhibited by freezing a customer's week's supply of packaged meals in cardboard boxes.

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Roast beef and its jus prepared in foodservice establishments are often implicated as vehicles of foodborne illness. Preparation practices that could contribute to survival or growth of foodborne disease bacteria were examined. Temperatures were reached during cooking that would kill vegetative forms of these organisms.

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Roast beef preparation practices were examined in eight foodservice establishments for the likelihood of contamination and the possibilities of survival or growth during each step of the operations. Clostridium perfringens was isolated from raw beef, equipment, and cooked beef. Staphylococcus aureus was isolated from raw beef, equipment, workers' hands, and cooked beef.

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