Effect of Relocation, Social Housing Changes, and Diarrhea Status on Microbiome Composition of Juvenile Cynomolgus Macaques ().

Social housing changes are likely stressful and can be associated with diarrhea, the most common health problem noted in captive macaque populations. Diarrhea may reflect a negative shift in the gut flora ("gut dysbiosis"). This study reported on changes in the gut microbiome composition of juvenile primates () that experienced a change in social housing and exhibited diarrhea.

Opioid and other drug use and drug-related mortality as indicators of Hepatitis C and Human Immunodeficiency Virus in Oklahoma.

Objectives: Outbreaks of injection drug use (IDU)-associated infections have become major public health concerns in the era of the opioid epidemic. This study aimed to (1) identify county-level characteristics associated with acute HCV infection and newly diagnosed IDU-associated HIV in Oklahoma and (2) develop a vulnerability index using these metrics.

Methods: This study employs a county-level ecological design to examine those diagnosed with acute or chronic HCV or newly diagnosed IDU-associated HIV.

Factor Xa Inhibitors versus warfarin in patients with morbid obesity and atrial fibrillation.

Purpose: Factor Xa Inhibitors have emerged as a first-line agent in the management of non-valvular atrial fibrillation (NVAF), but there is a need for additional data surrounding their use in the morbidly obese population. The purpose of this study was to evaluate whether Factor Xa Inhibitors are as safe and effective as warfarin for the treatment of NVAF in individuals with a BMI ≥ 40 kg/m and/or weight ≥ 120 kg.

Methods: This was a multi-center retrospective cohort study comparing the use of Factor Xa Inhibitors (apixaban and rivaroxaban) to warfarin for the management of NVAF in adult patients with a BMI ≥ 40 kg/m and/or weight ≥ 120 kg.

Carroll's Three-Stratum (3S) Cognitive Ability Theory at 30 Years: Impact, 3S-CHC Theory Clarification, Structural Replication, and Cognitive-Achievement Psychometric Network Analysis Extension.

Carroll's treatise on the structure of human cognitive abilities is a milestone in psychometric intelligence research. Thirty years later, Carroll's work continues to influence research on intelligence theories and the development and interpretation of intelligence tests. A historical review of the relations between the 3S and CHC theories necessitates the recommendation that the theories of Cattell, Horn, and Carroll be reframed as a family of obliquely correlated CHC theories-not a single CHC theory.

A Psychometric Network Analysis of CHC Intelligence Measures: Implications for Research, Theory, and Interpretation of Broad CHC Scores "Beyond ".

For over a century, the structure of intelligence has been dominated by factor analytic methods that presume tests are indicators of latent entities (e.g., general intelligence or ).

Underwater hearing in sea ducks with applications for reducing gillnet bycatch through acoustic deterrence.

As diving foragers, sea ducks are vulnerable to underwater anthropogenic activity, including ships, underwater construction, seismic surveys and gillnet fisheries. Bycatch in gillnets is a contributing source of mortality for sea ducks, killing hundreds of thousands of individuals annually. We researched underwater hearing in sea duck species to increase knowledge of underwater avian acoustic sensitivity and to assist with possible development of gillnet bycatch mitigation strategies that include auditory deterrent devices.

Linguistic Influences on Cognitive Test Performance: Examinee Characteristics Are More Important than Test Characteristics.

Consideration of the influence of English language skills during testing is an understandable requirement for fair and valid cognitive test interpretation. Several professional standards and expert recommendations exist to guide psychologists as they attempt to engage in best practices when assessing English learners (ELs). Nonetheless, relatively few evidence-based recommendations for practice have been specified for psychologists.

Drugs and bugs: Negative affect, psychostimulant use and withdrawal, and the microbiome.

Background And Objectives: A growing body of literature demonstrates that the human microbiota plays a crucial role in health and disease states, as well as in the body's response to stress. In addition, the microbiome plays a role in psychological well-being and regulating negative affect. Regulation of negative affect is a factor in psychostimulant abuse disorders.

Evaluation of the Cherokee Nation Hepatitis C Virus Elimination Program in the First 22 Months of Implementation.

Importance: In 2019, hepatitis C virus (HCV) infection contributed to more deaths in the US than 60 other notifiable infectious diseases combined. The incidence of and mortality associated with HCV infection are highest among American Indian and Alaska Native individuals.

Objective: To evaluate the association of the Cherokee Nation (CN) HCV elimination program with each element of the cascade of care: HCV screening, linkage to care, treatment, and cure.

Misclassification Error-Adjusted Prevalence of Injection Drug Use Among Infective Endocarditis Hospitalizations in the United States: A Serial Cross-Sectional Analysis of the 2007-2016 National Inpatient Sample.

Administrative health databases have been used to monitor trends in infective endocarditis hospitalization related to nonprescription injection drug use (IDU) using International Classification of Diseases (ICD) code algorithms. Because no ICD code for IDU exists, drug dependence and hepatitis C virus (HCV) have been used as surrogate measures for IDU, making misclassification error (ME) a threat to the accuracy of existing estimates. In a serial cross-sectional analysis, we compared the unadjusted and ME-adjusted prevalences of IDU among 70,899 unweighted endocarditis hospitalizations in the 2007-2016 National Inpatient Sample.

Validity of International Classification of Diseases codes in identifying illicit drug use target conditions using medical record data as a reference standard: A systematic review.

Background: The twenty-first century opioid crisis has spurred interest in using International Classification of Diseases (ICD) code algorithms to identify patients using illicit drugs from administrative healthcare data. We conducted a systematic review of studies that validated ICD code algorithms for illicit drug use against a reference standard of medical record data.

Methods: Systematic searches of MEDLINE, EMBASE, PsycINFO, and Web of Science were conducted for studies published between 1980 and 2018 in English, French, Italian, or Spanish.

Effect Modification of the Association Between Race and Stage at Colorectal Cancer Diagnosis by Socioeconomic Status.

Objectives: To compare risks of distant-stage colorectal cancer (CRC) diagnosis between whites and American Indian/Alaska Natives (AI/ANs) and to explore effect modification by area-based socioeconomic status (SES).

Design: Retrospective cohort study using data from the Oklahoma Central Cancer Registry.

Setting: Oklahoma.

General fluid/inductive reasoning battery for a high-ability population.

The validity of studies investigating interventions to enhance fluid intelligence (Gf) depends on the adequacy of the Gf measures administered. Such studies have yielded mixed results, with a suggestion that Gf measurement issues may be partly responsible. The purpose of this study was to develop a Gf test battery comprising tests meeting the following criteria: (a) strong construct validity evidence, based on prior research; (b) reliable and sensitive to change; (c) varying in item types and content; (d) producing parallel tests, so that pretest-posttest comparisons could be made; (e) appropriate time limits; (f) unidimensional, to facilitate interpretation; and (g) appropriate in difficulty for a high-ability population, to detect change.

Sir2 blocks extreme life-span extension.

Sir2 is a conserved deacetylase that modulates life span in yeast, worms, and flies and stress response in mammals. In yeast, Sir2 is required for maintaining replicative life span, and increasing Sir2 dosage can delay replicative aging. We address the role of Sir2 in regulating chronological life span in yeast.

A confirmatory analysis of the factor structure and cross-age invariance of the Wechsler Adult Intelligence Scale-Third Edition.

In the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III; D. Wechsler, 1997), the manual reports several confirmatory factor analyses in support of the instrument's latent factor structure. In practice, examiners frequently compare an examinee's score from a current administration of the WAIS-III with the results from a previous test administration.

Daughters' caregiving decisions: from an impulse to a balancing point of care.

Daughters comprise 29% of all caregivers of the dependent elderly and make decisions about parent care in a context of ambiguous and changing role expectations. This qualitative study explored the decision process of ten caregiving daughters. The women responded to parent dependency with an impulse to care and pursued a balancing point of care in the face of limiting decision conditions.

Response to Mathias and Nettelbeck on the structure of competence: need for theory-based methods to test theory-based questions.

In this paper, we respond to a 1992 study by Mathias and Nettelbeck in which, using exploratory factor analysis, they argued that the structure of intelligence in persons with mental retardation deviates from the model previously proposed by Greenspan. Applying the LISREL method of confirmatory factor analysis to Mathias and Nettelbeck's original correlation matrix, we found the Greenspan model (in which social and practical intelligence form separate factors) to be an equally plausible interpretation of their data as the single (Interpersonal Competence) factor found by Mathias and Nettelbeck. The fundings are discussed with respect to (a) the importance of using theory-based methods when addressing theory-based questions and (b) the role of social intelligence in the ongoing controversy over the meaning of mental retardation.

Community integration of young adults with mental retardation: a multivariate analysis of adjustment.

The purpose of the present study was to determine whether differences in community adjustment existed for three groups of young adults with mental retardation using data organized on the basis of four empirically validated factors identified in prior research. A descriptive discriminant function analysis was used as a follow-up to a statistically significant multivariate analysis of variance F-ratio. Results obtained from the discriminant analysis indicated that five variables (number of limiting factors, earned income, number of support services, living arrangement, number of daytime activities) contributed substantively to separation of the three group centroids.

Relationship between measures of adaptive functioning and community adjustment for adults with mental retardation.

This study investigated the concurrent relations between measures of adaptive/maladaptive behavior and community adjustment in a sample of 239 adults with mild to severe degrees of mental retardation. Using canonical correlation procedures and multidimensional community adjustment measures, the investigators found significant relations between the measures of behavior and several community adjustment dimensions. The results provided evidence for the criterion-related validity of measures of adaptive/maladaptive behavior and suggested that such skills provide an important contribution to community adaptation and to program planning and decision making for individuals with mental retardation.

Empirical analysis of multidimensional measures of community adjustment for young adults with mental retardation.

Confirmatory factor analysis procedures were used to evaluate multidimensional measures of community adjustment in a sample of 239 young adults with mild to severe mental retardation. Alternative measurement models were evaluated in one-half of the sample, with the final model cross-validated in the second half of the sample. The final cross-validated model was also evaluated as a function of level of retardation.

Components of personal competence and community integration for persons with mental retardation in small residential programs.

This study identifies components of personal competence and community adjustment in a national sample of persons with mental retardation living in residential facilities of six or fewer residents. Factor analysis of 65 variables yielded an 8 principal component solution that accounted for approximately half the total variance in the observed variables (49%). The eight identified components of personal competence and community adjustment were labeled (1) Self Care and Functional Personal Living Skills, (2) Community Living Skills, (3) Home Living Skills, (4) Problem Behavior, (5) Community Training Goals and Objectives, (6) Recreation/Leisure Activity, (7) Family Contact/Relationships, and (8) Community Assimilation and Acceptance.

Factor structure of maladaptive behavior across the lifespan of persons with mental retardation.

Data obtained on a sample of persons with mild to profound degrees of mental retardation (N = 8255) and ranging from birth to 98 years of age were factor analyzed to provide information on the structure of maladaptive behavior relative to age and degree of mental retardation. Using the Problem Behavior scales of the Inventory for Client and Agency Planning, two principal factors emerged for children with mild to profound degrees of retardation: Internalized Maladaptive and Externalized Maladaptive. For adolescents and young adults, a three-factor solution which varied by degree of retardation was most appropriate.