Publications by authors named "McDonnell C"

Many labels are used within and across subfields to describe personality disorder (PD) and interpersonally-oriented trait dimensions. For example, "interpersonal disorders" is a suggested alternative label to "personality disorders" in clinical research. Other "dark trait" terms, though not proposed as formal labels for PDs, also are used in different research areas for describing externalizing traits.

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Background: PATHFINDER was a prospective cohort study of multicancer early detection (MCED) testing in an outpatient ambulatory population. The aim of this study is to report the patient-reported outcomes (PROs) collected as secondary and exploratory measures in the PATHFINDER study.

Methods: PATHFINDER is a prospective, multicentre, cohort study that enrolled existing healthy ambulatory outpatients at seven health networks in the USA, including hospitals, academic medical centres, and integrated health systems.

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Maternal depression has been linked with increased risk of childhood obesity. Furthermore, maternal negative affectivity in early childhood has been associated with food fussiness. We explored the relationship between longitudinal maternal well-being mid-pregnancy, at 2 years and 5 years postpartum and children's appetitive traits at 5 years of age.

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Purpose: The purpose of this study was to investigate adolescent perspectives of parent-adolescent communication, type 1 diabetes mellitus (T1DM)-specific family conflict, self-efficacy, and their relationship to adolescent self-management of T1DM.

Methods: A cross-sectional survey design was employed. Adolescents completed measures of parent-adolescent communication, T1DM-specific family conflict, self-efficacy, and self-management, which included activation and division of responsibility for management tasks.

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Purpose: Autistic adults experience high rates of traumatic events and PTSD. However, little work has evaluated motor vehicle accident (MVA) related trauma symptoms. The goal of this brief report was to provide pilot data characterizing MVA-related peritraumatic reactions, trauma symptoms, and rates of PTSD diagnosis and mental health service use among Autistic compared to non-autistic adults.

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Lone mothers have been found to report lower average mental health than partnered mothers. Following the 'stress process model', disparities in women's mental health by family structure could be explained by lone mothers' higher exposure to multiple forms of stressors, compared to partnered mothers. Yet, this hypothesis has not been tested in previous studies.

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Introduction: Robotic surgery is typically characterized by the telemanipulation of robotic arms controlled by a surgeon via a command system. Medical technology advancements have caused variations in how robotic surgery is conceptualised. It is important to ascertain the public's perception of robotic surgery, as this impacts decision making.

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Iron homoeostasis is tightly regulated, with hepcidin and soluble transferrin receptor (sTfR) playing significant roles. However, the genetic determinants of these traits and the biomedical consequences of iron homoeostasis variation are unclear. In a meta-analysis of 12 cohorts involving 91,675 participants, we found 43 genomic loci associated with either hepcidin or sTfR concentration, of which 15 previously unreported.

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Article Synopsis
  • - The study investigates how oral sensory hypersensitivity and social-emotional responses in typically developing preteen children relate to their eating behaviors, especially focusing on traits like fussy eating and desire to drink.
  • - Using data from 130 mother-child pairs, researchers employed established sensory profile assessments and a children's eating behavior questionnaire to analyze the connections between child and maternal sensory processing traits.
  • - Results showed that children with higher oral sensory processing sensitivity often exhibited increased food fussiness and a greater desire to drink, while maternal sensory profiles revealed significant correlations with their children's sensory traits, indicating a shared sensory processing influence.
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  • Primary care providers (PCPs) struggle with disorganized information in electronic health records (EHR) while managing patients with chronic pain, which can be improved with clinical decision support (CDS) tools like the Chronic Pain OneSheet, designed to streamline patient information and support treatment decisions.
  • In a study involving interviews with PCPs who use OneSheet, barriers such as limited time, resistance to new workflows, and complex displays were identified, while facilitators included its role as a central data hub and ease of access to important features.
  • Recommendations to enhance OneSheet usage include simplifying displays, customizing features, and allowing broader access for patients and team members, emphasizing the need for CDS tools to align with PCP workloads and tasks.
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Objectives: Between the Irish late medieval (AD 1150-c.1550) (LMP) and post-medieval (AD c.1550-1800) (PMP) periods, colonial practices changed land ownership.

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There is growing interest in the roles of temperature, epidermal hydration (EH) and pain in pressure ulcer (PU) development. Investigating correlations between these measures and sub-epidermal moisture (SEM) will address this knowledge deficit. A prospective observational study enrolled 60 surgical patients from February to November 2021.

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. Optical fibre dosimeters (OFDs) offer great promise for real-timedose measurement in radiation-based treatment modalities such as radiotherapy and brachytherapy. This is attributed to their many useful qualities such as high spatial resolution and sensitivity.

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Background: Autistic adults experience high rates of traumatic events and posttraumatic stress disorder (PTSD) symptoms. However, less is known about how autistic adults experience (i.e.

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Background: Macrosomia (birthweight ≥4 kg) may alter the associations of physical activity (PA) and screen time (ST) throughout childhood with later cardiometabolic risk.

Objective: To investigate associations of PA and ST over a 4-6-year follow-up period with cardiometabolic outcomes in preteens (9-11-year-olds) who were born to mothers with previous macrosomic delivery.

Methods: This is an analysis of 402 preteens from the ROLO study, who were born to mothers that previously delivered an infant with macrosomia.

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Background: Childhood represents a critical period of nutritional risk in the programming of later chronic disease. Few longitudinal studies have explored repeated measures of nutrition throughout the first decade of life in relation to preteen cardiometabolic outcomes.

Objectives: This research aimed to explore associations of early feeding practices (human milk exposure and duration and timing of introduction to solids) and childhood dietary quality and inflammatory scores (at 5 and 9-11 y and change during childhood) on preteen cardiometabolic outcomes.

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Biocompatible fluorescent agents are key contributors to the theranostic paradigm by enabling real-time in vivo imaging. This study explores the optical properties of phenylenediamine carbon dots (CDs) and demonstrates their potential for fluorescence imaging in cells and brain blood vessels. The nonlinear absorption cross-section of the CDs was measured and achieved values near 50 Goeppert-Mayer (GM) units with efficient excitation in the 775-895 nm spectral range.

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Despite the decades of international climate negotiations and several landmark agreements, global efforts to date to restrict fossil fuel production in line with climate targets have been unsuccessful. As national and international policies continue to fall short of phasing out fossil fuels, increasing attention has been paid to non-state actors, like pension funds, as a potential source of more ambitious climate action. As major asset owners, large shareholders in fossil fuel companies, and historically activist investors, pension funds are theoretically well-placed to contribute to phasing out fossil fuels.

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Background: We explored change in child appetitive traits from 5 to 9-11 years old and examined associations between appetitive traits at both timepoints and child diet quality.

Methods: This is secondary analyses of the ROLO longitudinal birth cohort study, including mother-child dyads from the 5 and 9-11-year old follow-up. The Children's Eating Behaviour Questionnaire measured child appetitive traits, with 167 children having matched data for both timepoints.

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Institutional investors, who control as much as $154 trillion globally, may play an important role in shaping the energy transition as major stakeholders in fossil fuel producing, distributing and consuming companies. Research on investors and fossil fuels has focused largely on the divestment movement or on shareholder engagement. However, given their limited success to date, additional strategies to influence the fossil fuel sector are merited.

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Article Synopsis
  • Heterozygous mutations in the insulin receptor gene (INSR) lead to type A insulin resistance, causing issues like insulin resistance, high blood sugar levels, and reproductive problems in women.
  • The case study focuses on a 20-year-old woman with a specific insulin receptor mutation (p.Met1180Lys), who experiences symptoms like excessive hair growth, irregular menstrual cycles, and diabetes alongside other autoimmune diseases.
  • During her 11 pregnancies, she managed her diabetes with varying insulin doses, observing that her children with the mutation tended to have lower birth weights compared to those without it.
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The correlation between sub-epidermal moisture (SEM) and other early indicators of pressure ulcer (PU) development is yet to be determined. This three-part series aims to bridge this knowledge gap, through investigating SEM and its correlation with evidence-based technologies and assessments. This article focuses on the correlation between SEM and ultrasound.

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Background: Microplastics (MPs) are found in all environments: aquatic, airborne, and terrestrial. While their presence is not disputed, their potential impacts are not yet known.

Objective: To undertake a pilot analysis of MP contamination in archaeological sediment samples, taken in the late 1980s from two archaeological excavation sites in the historic city of York (UK) as well as contemporary sources close to the same sites, with respect to the presence (if any), levels, and characteristics of any particles identified.

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Objectives: Eating disorders are serious psychiatric conditions that affect people of all ages. Many psychiatry trainees' first and only experience with eating disorders during training is their Child and Adolescent Psychiatry (CAP) rotation. This study aimed to explore the learning experience of psychiatry trainees working within an Eating Disorder Program (EDP) during their CAP rotation.

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We experimentally demonstrate the generation of double terahertz (THz) pulses with tailored angular-dependent time delays from a nonlinear metasurface excited by a near-infrared femtosecond pulse. The tailored temporal properties of the generated pulses emerge from a direct mapping of the nonlinear spatial response of the metasurface to the emitted THz temporal profile. We utilize the Pancharatnam-Berry phase to implement symmetric and antisymmetric metasurface configurations and show that the emitted patterns present spatiotemporal "X-shaped" profiles after collimation by a parabolic mirror, with angular-dependent pulse delays corresponding to the intended design.

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