Publications by authors named "McCall E Torpey"
Importance: Hidradenitis suppurativa (HS) is a debilitating follicular skin disorder in which bacterial colonization is typical. Oral antibiotic efficacy can be unreliable; however, selective intravenous antibiotics, specifically ertapenem, may provide favorable clinical outcomes.
Objective: To explore optimal course duration, efficacy, and patient satisfaction associated with intravenous ertapenem for HS.
Article Synopsis
- * Research shows that patients with intellectual and developmental disabilities (IDD) experience HS more frequently and at a younger age compared to those without IDD.
- * A study at Albert Einstein College of Medicine-Montefiore HS Center analyzed 22 HS patients with IDD, revealing that diverse treatments such as antibiotics, hormonal therapies, and surgery are critical for managing the condition effectively.
Article Synopsis
- Efficacy of Adalimumab
- : A study of 57 hidradenitis suppurativa patients shows that adalimumab is significantly more effective in patients with a BMI under 30, leading to notable improvements in disease severity and inflammation markers.
- Impact of Obesity
- : Patients with a BMI of 30 or higher displayed increases in disease severity and inflammatory markers after treatment, indicating that obesity negatively affects the treatment's effectiveness.
- Need for Further Research
- : The findings suggest a need for more studies to explore how weight affects biologic treatment outcomes for hidradenitis suppurativa, emphasizing the importance of considering BMI in future treatment plans.