Prospective motion correction improves diagnostic utility of pediatric MRI scans.

A new technique for prospectively correcting head motion (called PROMO) during acquisition of high-resolution MRI scans has been developed to reduce motion artifacts. To evaluate the efficacy of PROMO, four T1-weighted image volumes (two with PROMO enabled, two uncorrected) were acquired for each of nine children. A radiologist, blind to whether PROMO was used, rated image quality and artifacts on all sagittal slices of every volume.

Automated white-matter tractography using a probabilistic diffusion tensor atlas: Application to temporal lobe epilepsy.

Diffusion-weighted magnetic resonance imaging allows researchers and clinicians to identify individual white matter fiber tracts and map their trajectories. The reliability and interpretability of fiber-tracking procedures is improved when a priori anatomical information is used as a guide. We have developed an automated method for labeling white matter fiber tracts in individual subjects based on a probabilistic atlas of fiber tract locations and orientations.

Subcortical and cerebellar atrophy in mesial temporal lobe epilepsy revealed by automatic segmentation.

Purpose: To determine the validity and utility of using automated subcortical segmentation to identify atrophy of the hippocampus and other subcortical and cerebellar structures in patients with mesial temporal lobe epilepsy (MTLE).

Methods: Volumetric MRIs were obtained on 21 patients with MTLE (11 right, 10 left) and 21 age- and gender-matched healthy controls. Labeling of subcortical and cerebellar structures was accomplished using automated reconstruction software (FreeSurfer).

Regional neocortical thinning in mesial temporal lobe epilepsy.

Purpose: To determine the nature and extent of regional cortical thinning in patients with mesial temporal lobe epilepsy (MTLE).

Methods: High-resolution volumetric MRIs were obtained on 21 patients with MTLE and 21 controls. Mean cortical thickness was measured within regions of interest and point-by-point across the neocortex using cortical reconstruction and parcellation software.

Neuropathic arthropathy of the foot with and without superimposed osteomyelitis: MR imaging characteristics.

Purpose: To determine retrospectively the magnetic resonance (MR) findings associated with pedal neuropathic arthropathy with and without superimposed osteomyelitis and to identify any useful discriminating features.

Materials And Methods: Investigational review board approval was obtained and allowed review of records and images without informed consent. HIPAA compliance was observed.