Strategies for coping with stress, emotional control and occupational burnout among surgical nurses.

Introduction And Objective: Nursing staff constitute 59% of the total number of health care workers worldwide - a total of 27.9 million people. The aim of the study is assessment of the prevalence of stress, including strategies for coping with stress, emotional control, and occupational burnout syndrome, as well as the effect of chronic stress on occupational burnout among surgical nurses.

Postsurgical tactile-evoked pain: a role for brain-derived neurotrophic factor-tropomyosin receptor kinase B-dependent novel tactile corpuscles.

Introduction: Millions of people undergo surgical procedures each year with many developing postsurgical pain. Dynamic allodynia can arise when, for example, clothing brushing close to the surgical site elicits pain. The allodynia circuits that enable crosstalk between afferent tactile inputs and central pain circuits have been studied, but the peripheral tactile drive has not been explored.

Environmental pollution and extreme weather conditions: insights into the effect on mental health.

Environmental pollution exposures, including air, soil, water, light, and noise pollution, are critical issues that may implicate adverse mental health outcomes. Extreme weather conditions, such as hurricanes, floods, wildfires, and droughts, may also cause long-term severe concerns. However, the knowledge about possible psychiatric disorders associated with these exposures is currently not well disseminated.

The Effect of Hyperbaric Storage on the Nutritional Value and Retention of Certain Bioactive Proteins in Human Milk.

Human milk (HM) contains the essential macronutrients and bioactive compounds necessary for the normal growth and development of newborns. The milk collected by human milk banks is stored frozen and pasteurized, reducing its nutritional and biological value. The purpose of this study was to determine the effect of hyperbaric storage at subzero temperatures (HS-ST) on the macronutrients and bioactive proteins in HM.

Impact of Nutritional Status of Patients with Head and Neck Squamous Cell Carcinoma on the Expression Profile of Ghrelin, Irisin, and Titin.

The goal of this paper was the evaluation of the changes in the expression profile of irisin, ghrelin, and titin in the carcinoma tissue and in the blood of patients with head and neck squamous cell carcinoma (HNSCC), including determining the profile of their expression in relation to patient nutrition. The study included 56 patients with diagnosed squamous cell carcinoma of HNSCC in the T3 and T4 stages of the disease. Healthy control tissue specimens were collected from an area 10 mm outside the histologically negative margin.

Using Follow-Up Telephone Calls to Identify Obstacles to Prevention and Treatment of Chemotherapy-Induced Nausea and Vomiting.

Background: Despite advances in antiemetic regimens, uncontrolled chemotherapy-induced nausea and vomiting (CINV) remains a problem for patients receiving oncology treatment, leading to decreased quality of life and worse treatment outcomes.

Objectives: The purpose of this pilot project was to use follow-up telephone calls to identify barriers related to successful management and prevention of CINV on a single-center outpatient chemotherapy infusion unit.

Methods: A mixed-methods descriptive design was used for this project.

The smell of death. State-of-the-art and future research directions.

The decomposition of a body is inseparably associated with the release of several types of odors. This phenomenon has been used in the training of sniffer dogs for decades. The odor profile associated with decomposition consists of a range of volatile organic compounds (VOCs), chemical composition of which varies over time, temperature, environmental conditions, and the type of microorganisms, and insects colonizing the carcass.

Characteristics, Mortality, and Clinical Outcomes of Hospitalized Patients with COVID-19 and Diabetes: A Reference Single-Center Cohort Study from Poland.

Background: Diabetes is a risk factor for a severe course of COVID-19. We evaluated the characteristics and risk factors associated with undesirable outcomes in diabetic patients (DPs) hospitalized due to COVID-19.

Materials And Methods: The data analysis of patients admitted between March 6, 2020, and May 31, 2021, to the University Hospital in Krakow (Poland), a reference center for COVID-19, was performed.

Type 1 diabetes outpatient care and treatment effectiveness during COVID-19: A single-center cohort study.

Purpose: COVID-19 has brought many challenges for providing quality healthcare for type 1 diabetes (T1DM). We evaluated the impact of the COVID-19 pandemic on the medical care, glycemic control, and selected outcomes in T1DM patients.

Methods: We retrospectively analyzed medical records from 357 T1DM adults enrolled in the Program of Comprehensive Outpatient Specialist Care at the University Hospital in Krakow, and assessed differences in patient data from before the COVID-19 period (March 2019-February 2020) and after it started COVID-19 (March 2020-February 2021).

The experiences of UK-based genetic counsellors working in mainstream settings.

Most UK-based genetic counsellors (GCs) work within clinical genetics services; yet there is a small and expanding group of GCs working within other clinical specialties, termed "mainstream" GCs. To our knowledge there have been no projects to date examining the experiences of mainstream GCs working in the UK. The aim of this workforce evaluation was to explore the experiences of mainstream GCs.

OLHA (N-oleoylhistamine) modulates activity of mouse brain histaminergic neurons.

Histaminergic (HA) neurons are located in the tuberomamillary nucleus (TMN) of the posterior hypothalamus, from where they project throughout the whole brain to control wakefulness. We examined the effects of N-oleoylhistamine (OLHA), a non-enzymatic condensation product of oleic acid (OLA) and histamine, on activity of mouse HA neurons in brain slices. OLHA bidirectionally modulated the firing of HA neurons.

Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β adrenergic agonist.

Metabolic reprogramming contributes to oncogenesis, tumor growth, and treatment resistance in pancreatic ductal adenocarcinoma (PDAC). Here we report the effects of (R,S')-4'-methoxy-1-naphthylfenoterol (MNF), a GPR55 antagonist and biased β-adrenergic receptor (β-AR) agonist on cellular signaling implicated in proliferation and metabolism in PDAC cells. The relative contribution of GPR55 and β-AR in (R,S')-MNF signaling was explored further in PANC-1 cells.

Analysis of the Effect of Photo and Hydrodegradation on the Surface Morphology and Mechanical Properties of Composites Based on PLA and PHI Modified with Natural Particles.

Biodegradable polymer materials are increasingly used in the packaging industry due to their good properties and low environmental impact. Therefore, the work was performed on the injection molding of the bio-based composites of polylactide (PLA) and polyhydroxyalcanates (PHI) modified with two phases: reinforcing (walnut shell flour and cellulose) and coloring (beta carotene and anthocyanin). The produced materials were subjected to wide mechanical characteristics-tensile, flexural, and fatigue tests.

Tachykinins amplify the action of capsaicin on central histaminergic neurons.

Substance P (SP), a product of the tachykinin 1 (Tac1) gene, is expressed in many hypothalamic neurons. Its wake-promoting potential could be mediated through histaminergic (HA) neurons of the tuberomamillary nucleus (TMN), where functional expression of neurokinin receptors (NKRs) waits to be characterized. As in the process of nociception in the peripheral nervous system (PNS) capsaicin-receptor (transient potential vanilloid 1: TRPV1) signalling is amplified by local release of histamine and SP, we tested the involvement of tachykinins in the capsaicin-induced long-lasting enhancement (LLEcaps) of HA neurons firing by investigating selective neurokinin receptor ligands in the hypothalamic mouse brain slice preparation using patch-clamp recordings in cell-attached mode combined with single-cell RT-PCR.

Task measuring implicit attractiveness as a function of skin tone and facial features: a failed replication.

In two studies, participants completed an implicit attractiveness task with faces as primes varying on (a) facial features from Afrocentric to Eurocentric and (b) skin tone from dark to light, and target pictures of environmental scenes varying in attractiveness. On each trial, participants were briefly primed with a face. Next, they categorized a target picture as either or as quickly as possible.

Preliminary investigation of two promoter region polymorphisms of the gene in patients with recurrent depressive disorder.

Immune system dysregulation plays a role in the pathogenesis of complex human diseases, including psychiatric disorders. In addition, elevated levels of pro-inflammatory cytokines, including tumor necrosis factor α (TNF-α) may be conditioned by the presence of specific polymorphic variants. The present case-controlled preliminary study evaluated the prevalence of gene single nucleotide polymorphisms (SNPs) G-308A (rs1800629) and T-1031C (rs1799964) in 83 Polish patients with depression by restriction fragment length polymorphism analysis.

Electron Beam-Treated Enzymatically Mineralized Gelatin Hydrogels for Bone Tissue Engineering.

Biological hydrogels are highly promising materials for bone tissue engineering (BTE) due to their high biocompatibility and biomimetic characteristics. However, for advanced and customized BTE, precise tools for material stabilization and tuning material properties are desired while optimal mineralisation must be ensured. Therefore, reagent-free crosslinking techniques such as high energy electron beam treatment promise effective material modifications without formation of cytotoxic by-products.

Emission of harmful gases from animal production in Poland.

The aim of the study was to present the scale of greenhouse gas emissions from animal production, and to provide test results from different housing systems. In three free stall buildings, two with slurry in deep channels and one with cattle in cubicles staying on shallow litter concentration of ammonia and carbon dioxide were measured in summer season by using dedicated equipment from Industrial Scientific Research. Air exchange was calculated on the base of balance carbon dioxide method.

Vibroacoustical Performance Analysis of a Rigid Device Casing with Piezoelectric Shunt Damping.

Noise and vibration are common issues that may have a negative impact on human's' health. To minimize their consequences, several vibroacoustical methods may be employed. One well-known method is Piezoelectric Shunt Damping (PSD).

Mechanical Behavior and Morphological Study of Polytetrafluoroethylene (PTFE) Composites under Static and Cyclic Loading Condition.

The key goal of this study was to characterize polytetrafluoroethylene (PTFE) based composites with the addition of bronze particles and mineral fibers/particles. The addition of individual fillers was as follows: bronze-30-60 wt.%, glass fibers-15-25 wt.