An epidemiological study of dentition status, treatment needs and correlation with the dietary and oral hygiene practices among school-going children population of West Bengal.

Introduction: The global burden of disease study 2016 estimated that oral diseases affected 3.58 billion people with dental caries. Severe tooth loss and total edentulous condition have been reported as one of the leading causes of years lived with disability in some high-income countries.

Interaction of tautomers of doxorubicin with guanine-cytosine base pair: a density functional theory study.

Context: Anthracycline anticancer antibiotics from Streptomyces peucetius show high affinity for nucleobases. This study uses quantum mechanical density functional theory (DFT) to investigate interactions between doxorubicin (DOX) tautomers and the guanine-cytosine (GC) base pair. Intermolecular distances and interaction energies reveal structural relationships and stabilization.

"Résorption radiculaire interne:" A case report on dual-phase management of extensive internal root resorption.

This case study delves into an uncommon occurrence of internal root resorption (IRR), an inflammatory variant with perforation of root, in the left central incisor, which seems to have a prevalence ranging from 0.01% to 1%. The patient presented with pain in the upper left front tooth, leading to a diagnosis of pulpal necrosis with symptomatic apical periodontitis.

analysis of compressive strength of root dentin on application of intracanal medicaments for different time periods.

Background: Extended application of intracanal medicaments such as calcium hydroxide (CH) and triple antibiotic paste (TAP) is documented to reduce dentin's resistance to fracture.

Aim: This study intended to evaluate the resistance to fracture of root dentin treated with different medicaments - CH, TAP, CH with chlorhexidine (CHX) and lycopene (LP), and chitosan acetate (CA) - over 7, 14, and 42 days.

Materials And Methods: Seventy-five single-rooted human mandibular premolars were biomechanically prepared and categorized into five groups based on the medicament used, with further subdivision based on application duration.

Comparative Evaluation of Microleakage in Class V Cavities Restored with Newer Bioactive Restorative Materials: Activa Bioactive Restorative and Activa Pronto.

Aim: To compare the microleakage in class V cavities restored with Activa Bioactive Restorative, Activa Pronto, and nanohybrid composite.

Materials And Methods: Standardized class V cavity preparations (mesiodistal: 3 mm; occlusocervical: 2 mm; axial depth: 1 mm) were made on the buccal surface of 60 extracted intact maxillary premolar teeth. The preparations were divided into three experimental groups ( = 20) depending on the restorative material used.

An In-Vitro Study of the Root Canal Configuration of Mandibular First Premolars in a Bengali Subpopulation Using Cone-Beam Computed Tomography.

Aim: This study aims to analyze the root canal configuration system of mandibular first premolars in the Bengali subpopulation using cone-beam computed tomography (CBCT).

Materials And Methods: Based on Vertucci's classification, the root canal morphology of 100 randomly selected mandibular first premolars in 56 males and 44 females from the Bengali subpopulation of West Bengal was assessed in vitro. The location of the apical foramen, lateral canal, C-shaped canal, types of canal orifice cross-sections, minor constriction diameter, tooth length, and root length were noted.

Quantitative analysis of antibacterial efficacy of herbal irrigants against endodontic microflora - A clinical study.

Aims: The study aimed to assess the antimicrobial effectiveness of green tea and neem extract compared to sodium hypochlorite (NaOCl) against various root canal microorganisms.

Materials And Methods: Thirty patients with pulpal necrosis were selected, providing 60 samples before and after irrigation. Groups were assigned as follows: Group A: 3% NaOCl (control), Group B: green tea, and Group C: neem extract.

Effect of ligand substituents on the reactivity pathways of copper(II) complexes towards electrocatalytic water oxidation.

The electrocatalytic water oxidation activity of three copper(II) complexes [Cu(L1H)(L)](ClO) (1), [Cu(L2H)(L)(HO)](ClO) (2) and [Cu(L3H)(L)](ClO) (3) with aryl oxime ligands L1H, L2H and L3H [L1H = 1-(pyridin-2-yl)methanone oxime, L2H = 1-(pyridin-2-yl)ethanone oxime and L3H = 1-(pyridin-2-yl)propanone oxime] was investigated. All the three ligands have in common a pyridyl group attached to the carbon centre of the oxime moiety and differ in the second substituent attached to the carbon centre. Electrochemical investigation of the catalytic activity of complexes 1, 2 and 3 shows that the nature of the substituent attached to the carbon centre has an influence on the catalytic pathway and overall catalytic activity of these complexes.

Enamel hypoplasia with nonsyndromic oligodontia: A rare case report.

Enamel hypoplasia is an exclusive ectodermal disturbance, related to alterations in the organic enamel matrix which can cause white flecks, narrow horizontal bands, lines of pits, grooves, and discoloration of the teeth. It can result in compromised oral health that causes physiological and psychological disturbances. Management of enamel hypoplasia not only includes esthetic and functional rehabilitation of the patient but also requires a positive rapport building with the patient due to psychosocial issues.

analysis and characterization of potential inhibitors of MmaA3, a methoxy mycolic acid synthase from .

The emergence of the multi-and extensively drug-resistant (MDR and XDR) strains of necessitates paradigm-shifting therapeutic approaches. The impermeable waxy lipid layer, primarily composed of mycolic acids, is a key factor in conferring resistance to conventional drugs. This study introduces a novel strategy to combat drug resistance by targeting Methoxy mycolic acid synthase 3 (MmaA3), a critical enzyme in the mycolic acid biosynthesis pathway.

Evaluating the potential of daily intake of polystyrene microplastics via drinking water in inducing PCOS and its ovarian fibrosis progression using female zebrafish.

Polystyrene microplastics, extensively considered endocrine disrupting chemicals, disturb the reproductive system of living organisms. Polycystic ovary syndrome (PCOS), the reproductive endocrinopathy, is longstanding concern due to its eternal impacts as reproductive disorder and infertility. Despite several reports in reproductive and endocrine toxicity, there is inadequate literature regarding the daily intake of polystyrene-microplastics via drinking water in causing PCOS and leading to ovarian fibrosis in long-term.

Adding value to banana farming: Antibody production in post-harvest leaves.

Banana, a globally popular fruit, is widely cultivated in tropical and sub-tropical regions. After fruit harvest, remaining banana plant materials are low-value byproducts, mostly composted or used as fibre or for food packaging. As an aim to potentially increase farmer income, this study explored underutilised banana biomass as a novel plant tissue for production of a high-value product.

Surface roughness and microhardness evaluation of composite resin restorations subjected to three different polishing systems immediately and after 24 h: An study.

Background: Finishing and polishing of composite resin restorations can be considered two different procedures or two steps of a single procedure. During the finishing procedure, contours are corrected while margins and irregularities are smoothened. The polishing procedures result in the production of a smooth and lustrous finish.

Behavioral Activation for Comorbid Depression in People With Noncommunicable Disease in India: Protocol for a Randomized Controlled Feasibility Trial.

Background: The increasing burden of depression and noncommunicable disease (NCD) is a global challenge, especially in low- and middle-income countries, considering the resource constraints and lack of trained human resources in these settings. Effective treatment of depression in people with NCDs has the potential to enhance both the mental and physical well-being of this population. It will also result in the effective use of the available health care resources.

A review of , a promising functional food and source of health-related phytochemicals.

is an edible herb, that is also used for traditional medical purposes. It is high in antioxidants, phenols, and flavonoids. However, there is limited information on the nutritional composition and the mechanisms by which nutritional and functional constituents of affect human metabolism.

Molecular analysis of dUTPase of for identification of novel inhibitors using studies.

The human gastric pathogen chronically affects the gastric mucosal layer of approximately half of world's population. The emergence of resistant strains urges the need for identification of novel and selective drug against new molecular targets. A ubiquitous enzyme, Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase), is considered as first line of defense against uracil mis-incorporation into DNA, and essential for genome integrity.

In silico identification and analysis of potential inhibitors for acid phosphatase, HppA from Helicobacter pylori.

Helicobacter pylori is the most common cause of gastric ulcers and is associated with gastric cancer. The enzyme HppA of class C nonspecific acid phosphohydrolases (NSAPs) of H. pylori plays a crucial role in the electron transport chain.

First Report of and Causing Bacterial Soft Rot on Curly Dwarf Pak Choy ( var. ) in Malaysia.

var. (curly dwarf pak choy) is commonly grown in large-scale vertical farming aquaponic systems. In October 2022, soft rot symptoms and dark brown lesions were observed on grown in a commercial aquaponic farm located in Perak, Malaysia.

IMPACT smoking cessation support for people with severe mental illness in South Asia (IMPACT 4S): A protocol for a randomised controlled feasibility trial of a combined behavioural and pharmacological support intervention.

Introduction: The prevalence of smoking is high among people living with severe mental illness (SMI). Evidence on feasibility, acceptability and effectiveness of smoking cessation interventions among smokers with SMI is lacking, particularly in low- and middle-income countries. We aim to test the feasibility and acceptability of delivering an evidence-based intervention,i.

Effectiveness of interventions to address obesity and health risk behaviours among people with severe mental illness in low- and middle-income countries (LMICs): a systematic review and meta analysis.

Introduction: People with severe mental illness (SMI) are more likely to have obesity and engage in health risk behaviours than the general population. The aims of this study are (1) evaluate the effectiveness of interventions that focus on body weight, smoking cessation, improving sleeping patterns, and alcohol and illicit substance abuse; (2) Compare the number of interventions addressing body weight and health risk behaviours in low- and middle-income countries (LMICs) . those reported in published systematic reviews focusing on high-income countries (HICs).

Minimal change disease (MCD) following vaccination with ChAdOx1 nCoV-19 vaccine in a young Indian male: A case report.

Various vaccines against coronavirus disease 2019 (COVID-19) have been developed amidst the ongoing pandemic. Few cases of glomerulonephritis after COVID-19 vaccination have been reported globally. We present a case of nephrotic syndrome due to minimal change disease (MCD) most likely associated with the ChAdOx1 nCoV-19 vaccine.

Comparative evaluation of adhesion of glass fiber post to the root dentin after surface treatment of post and using universal bonding agent: An study.

Objective: The purpose of the study is the evaluation and comparison of surface roughness and bond strength of glass fiber post (GFP) after different types of surface treatment and the application of a universal bonding agent.

Materials And Methods: Forty GFPs were divided into four groups based on surface treatment: Group I, silane coupling agent application for 60 s; Group II, air abrasion with 30 μm silicon dioxide powder particles in 2.5 bar pressure from 2 cm distance for 10 s, followed by silane coupling agent application; Group III, 9% hydrofluoric acid application for 10 s, rinsed and air-dried, followed by silane coupling agent application; and Group IV, silane coupling agent application, followed by universal bonding agent application.

Arbuscular Mycorrhizal Symbiosis: A Strategy for Mitigating the Impacts of Climate Change on Tropical Legume Crops.

Climate change is likely to have severe impacts on food security in the topics as these regions of the world have both the highest human populations and narrower climatic niches, which reduce the diversity of suitable crops. Legume crops are of particular importance to food security, supplying dietary protein for humans both directly and in their use for feed and forage. Other than the rhizobia associated with legumes, soil microbes, in particular arbuscular mycorrhizal fungi (AMF), can mitigate the effects of biotic and abiotic stresses, offering an important complementary measure to protect crop yields.