Clinical and Radiological Follow-Up of a Pfizer-BioNTech COVID-19 Vaccine-Induced Hemichorea-Hemiballismus.

Background: Hemichorea-hemiballismus is a rare hyperkinetic movement disorder.

Case Report: A 90-year-old male developed left hemichorea-hemiballismus after his second dose of the Pfizer-BioNTech COVID-19 vaccine. A wide range of investigations including magnetic resonance imaging did not reveal an alternative cause.

Mechanical Disintegration and Particle Size Sieving of (Irish Moss) Gametophytes and Their Effect on Carrageenan and Phycoerythrin Extraction.

To better understand the migration properties of hybrid carrageenan from the seaweed tissue during carrageenan extraction, the effect of increasing the seaweed surface area by the mechanical disintegration of gametophyte chips was studied under various temperature and time extraction conditions. Dried seaweed chips were milled by a rotor beater mill and classified into eight different size fractions by sieving with varying mesh sizes from 50 to 2000 μm. During extraction at 22 °C, the red color of the filtrate increased significantly with the decreasing particle size of the fraction, correlating with the increasing phycoerythrin concentration (from 0.

Neurological consequences of recreational nitrous oxide abuse during SARS-CoV-2 pandemic.

Introduction: Recreational use of nitrous oxide (NO) is a growing practice in France and all around the world and is often associated with neurological complications. We report detailed clinical and paraclinical presentations of 12 patients with combined degeneration of the spinal cord and peripheral neuropathies in relation to NO consumption, possibly favored by lockdowns due to SARS-CoV-2 pandemic.

Results: With variable levels of consumption, the 12 patients presented spinal cord and/or peripheral nerve damage, with mostly motor and ataxic symptoms, motor axonal nerve damage, and medullary T2-weighted hyperintensities on MRI.

Reintroduction of immune-checkpoint inhibitors after immune-related meningitis: a case series of melanoma patients.

Immune-checkpoint inhibitors (ICIs) targeting cytotoxic T lymphocyte-associated antigen-4 and programmed cell death ligand-1) are associated with several immune-related neurological disorders. Cases of meningitis related to ICIs are poorly described in literature and probably underestimated. Several guidelines are available for the acute management of these adverse events, but the safety of resuming ICIs in these patients remains unclear.

Mapping French people and health professionals' positions regarding the circumstances of morphine use to relieve cancer pain.

Background: Cancer patients suffer in part because some health professionals prescribe or administer amounts of analgesics, namely opioids, which are too small or too widely spaced to be fully effective. Patients' reluctance to use opioids for pain treatment is often mentioned as a reason not to apply the official guidelines, but very few studies have been conducted on people's attitudes about opioid use to relieve cancer pain.

Methods: One hundred twenty lay participants and 30 health professionals (7 physicians and 23 nurses) were presented with a set of vignettes describing a terminally ill woman with cancer who is in pain.

French laypeople's and health professionals' views on the acceptability of terminal sedation.

Aim: To study the views on the acceptability of terminal sedation (TS) of laypeople and health professionals in France.

Method: In November 2013-June 2015, 223 laypeople and 53 health professionals (21 physicians and 32) judged the acceptability of TS in 48 realistic scenarios composed of all combinations of four factors: (a) the patients' life expectancy, (b) their request for sedation, (c) the decision-making process and (d) the type of sedation. In all scenarios, the patients were women with a terminal illness suffering from intractable pain and receiving the best possible care.

Enzymatic degradation of hybrid iota-/nu-carrageenan by Alteromonas fortis iota-carrageenase.

Hybrid iota-/nu-carrageenan was water-extracted from Eucheuma denticulatum and incubated with Alteromonas fortis iota-carrageenase. The degradation products were then separated by anion-exchange chromatography. The three most abundant fractions of hybrid iota-/nu-carrageenan oligosaccharides were purified and their structures were analyzed by NMR.

Complete assignment of (1)H and (13)C NMR spectra of standard neo-iota-carrabiose oligosaccharides.

Standard Eucheuma denticulatum iota-carrageenan was degraded with the Alteromonas fortis iota-carrageenase. The most abundant products, the neo-iota-carratetraose and neo-iota-carrahexaose were purified by permeation gel chromatography, and their corresponding (1)H and (13)C NMR spectra were fully assigned.

Composition and distribution of carrabiose moieties in hybrid kappa-/iota-carrageenans using carrageenases.

Hybrid kappa/iota-carrageeans extracted from Gigartina skottsbergii, Chondracanthus chamissoï, and Chondrus crispus were incubated with Pseudoalteromonas carrageenovora kappa-carrageenase and Alteromonas fortis iota-carrageenase. The degradation products as well as the resistant fraction were fully characterized by chromatography, NMR, and mass spectrometry. The low percentage of degradation observed after treatment by the iota-carrageenase suggests that long segments of iota-carrabiose or block of iota-carrageenan are low in abundance.

Elucidation of the emulsification properties of sugar beet pectin.

A protocol has been developed to fractionate sugar beet pectin using hydrophobic affinity chromatography. Three samples eluted from the column using 4 M NaCl as solvent (fractions 1A, 1B, and 1C), two fractions eluted using 2 M NaCl (fractions 2A and 2B), and one fraction eluted using water (fraction 3). The fractions were shown to be very polydisperse, and differences between the GPC refractive index and UV absorbance (214 nm) elution profiles demonstrated chemical heterogeneity.

Contributions of reformatted computed tomography and panoramic radiography in the localization of third molars relative to the maxillary sinus.

Objective: The aim of this clinical study was to seek an answer to the question of whether CT gives better qualitative and quantitative information as compared to panoramic radiograph when deciding on extraction of upper impacted third molars.

Study: The study concerned 34 third molars appearing in direct relation with the sinus on the panoramic radiograph for which a CT scan had been recommended. For each case, the panoramic radiograph was compared with the CT scan for 5 evaluation criteria.

[Cortical thrombophlebitis and developmental venous anomalies].

Abnormal intracranial venous drainage called cerebral venous angioma is usually asymptomatic. Hemorrhages and seizures may however occur. The malformation may rarely be revealed by thrombosis.

Florid cemento-osseous dysplasia: Report of a case documented with computed tomography and 3D imaging.

Florid cemento-osseous dysplasia is an uncommon disease of the jaws. This article reports the case of a 49-year-old black woman who was diagnosed with florid cemento-osseous dysplasia on the basis of conventional radiographic findings. Computed tomography and three-dimensional imaging of the mandible were performed, and they enabled detailed localization of the bone defects.

[The facial approach to the median structures of the skull base].

Numerous routes of access to the medial basal structures of the cranium have been described, largely because of the wide variety of lesions observed in deep localizations. Access can be achieve via trans-sinusal, transfacial (trans-sphenoidal rhinoseptal, mediofacial or Lefort I), trans-oro-pharyngeal and numerous other routes. An examination of the principals involved, their development and the technical modalities demonstrate the advantages and disadvantages of each and their specific indications.

Osteoid osteoma: CT-guided percutaneous treatment.

Seven patients with presumed osteoid osteoma were treated with percutaneous destruction or drill resection with computed tomographic (CT) guidance. The diagnosis of osteoid osteoma was made on the basis of findings in the clinical history and results at plain radiography, bone scintigraphy, and CT. In four patients, histologic confirmation was obtained.

[Treatment of osteoid osteoma with percutaneous resection under computerized tomography control. Apropos of 5 cases].

Osteoid osteoma is a benign tumor requiring a surgical resection. An original technique is reported: the nidus was first located by computed tomography and then reached and resected through a small percutaneous approach. A special device, similar to those of knee arthroscopy or percutaneous discotomy has been designed.

[A thoracic "stealing" vascular syndrome (author's transl)].

The authors report quite a remarkable observation of a thoracic "stealing" vascular syndrome, apparently a sequela of a previous pleural involvement. It was a patient with fainting fits in effort related to severe hemo-diversion of the sub-pleural vascular laci fed by several vascular pedicles coming from the internal mammary artery and several broncho-intercostal arterial vessels. Selective bronchial arteriography revealed these pedicles, enabling an important blood derivation in effort without corresponding venous return, with a phenomenon of low cerebral outflow; a series of embolisms in these pedicles enabled to obtain a valuable obliteration of the main ones with a complete disappearance of the clinical signs.

Revascularization of the spinal cord by micro-anastomoses in dogs.

The severity of ischemic lesions in the spinal cord justifies attempts at its surgical revascularization. The experiments consisted of: (1) creating devascularization of the conus medullaris by ligation of all the lumbo-sacral collaterals of the aorta, and (2) revascularizing the lumbo-sacral rachidian circulation by performing an end-to-side anastomosis between the caudal mesenteric artery and the 5th left lumbar artery (from which in the dog the Adamkiewicz artery generally arises). After two-months, the patency rate of the 20 cases was 85%.